Lihat sumber Piala Italia 2021–2022

{{Infobox football tournament season
|title           = Piala Italia
|year            = 2021–2022
|other_titles    = 
|image           = 
|imagesize       = 
|caption         = 
|champions       = [[FC Internazionale Milano|Inter Milan]]<br>(gelar ke-8)
|count           = 
|runner-up       = [[Juventus]]
|matches         = 46
|goals           = 156
|top goal scorer = [[Dušan Vlahović]]<br>(4 gol)
|country         = Italia
|dates           = 7 Agustus 2021 – 11 Mei 2022
|num_teams       = 44
|updated         = 
|prevseason      = [[Piala Italia 2020–2021|2020–2021]]
|nextseason      = [[Piala Italia 2022–2023|2022–2023]]
}}
'''Piala Italia 2021–2022''' adalah edisi ke–75 [[Piala Italia]], kompetisi nasional [[sepak bola]] di Italia.<ref name="format">{{cite web|url=https://www.legaseriea.it/uploads/default/attachments/comunicati/comunicati_m/8855/files/allegati/8954/319_-_regolamento_coppa_italia_2021-2024.pdf|title=Coppa Italia: Regolamento|publisher=Lega Serie A|website=|language=it|accessdate=27 Juni 2021|date=8 Juni 2021|archive-date=2021-06-29|archive-url=https://web.archive.org/web/20210629222517/https://www.legaseriea.it/uploads/default/attachments/comunicati/comunicati_m/8855/files/allegati/8954/319_-_regolamento_coppa_italia_2021-2024.pdf|dead-url=yes}}</ref>

Jumlah tim yang berpartisipasi dikurangi dari 78 pada musim sebelumnya menjadi hanya 44 klub.<ref>{{Cite web|title=Coppa Italia, ecco il nuovo format della competizione|url=https://corrieredellosport.it/news/calcio/coppa-italia/2021/05/26-82066461/coppa_italia_ecco_il_nuovo_format_della_competizione|access-date=12 Juli 2021|website=CorrieredelloSport.it|language=it|date=26 Mei 2021}}</ref>

[[Juventus F.C.|Juventus]] adalah juara bertahan sebelum mereka dikalahkan [[FC Internazionale Milano|Inter Milan]] pada laga [[Final Piala Italia 2022|final]] dengan skor 4–2 setelah perpanjangan waktu. Kemenangan tersebut merupakan gelar juara Piala Italia Internazionale ke-8.<ref>{{cite web|url=https://football-italia.net/coppa-italia-final-juventus-2-4-inter-aet-thrilling-nerazzurri-triumph/|title=Coppa Italia Final – Juventus 2-4 Inter aet: Thrilling Nerazzurri Triumph|language=en|website=Football Italia|date=11 Mei 2022|access-date=11 Mei 2022}}</ref><ref>{{cite news|url=https://www.bbc.com/sport/football/61413085|title=Juventus 2–4 Inter Milan: Inter come from behind to win first Coppa Italia since 2011|language=en|work=BBC Sport|date=11 Mei 2022|access-date=11 Mei 2022}}</ref>

== Tim peserta ==
{| class="wikitable"
|- style="background:#D6E2B3; text-align:center; vertical-align:top;"
| style="width:33%" | '''Serie A'''<br>20 klub [[Serie A 2021–2022|musim 2021–2022]]
| style="width:33%" | '''Serie B'''<br>20 klub [[Serie B 2021–2022|musim 2021–2022]]
| style="width:34%" | '''Serie C'''<br>Empat klub [[Serie B 2021–2022|musim 2021–2022]] 
|- style="vertical-align:top"
|
* [[Atalanta B.C.|Atalanta]]
* [[Bologna F.C. 1909|Bologna]]
* [[Cagliari Calcio|Cagliari]]
* [[ACF Fiorentina|Fiorentina]]
* [[Empoli F.C.|Empoli]]
* [[Genoa C.F.C.|Genoa]]
* [[Hellas Verona F.C.|Hellas Verona]]
* [[FC Internazionale Milano|Inter Milan]]
* [[Juventus F.C.|Juventus]]
* [[S.S. Lazio|Lazio]]
* [[A.C. Milan|AC Milan]]
* [[S.S.C. Napoli|Napoli]]
* [[A.S. Roma|Roma]]
* [[U.S. Salernitana 1919|Salernitana]]
* [[U.C. Sampdoria|Sampdoria]]
* [[U.S. Sassuolo Calcio|Sassuolo]]
* [[Spezia Calcio|Spezia]]
* [[Torino F.C.|Torino]]
* [[Udinese Calcio|Udinese]]
* [[Venezia F.C.|Venezia]]
|
* [[U.S. Alessandria Calcio 1912|Alessandria]]
* [[Ascoli Calcio 1898 F.C.|Ascoli]]
* [[Benevento Calcio|Benevento]]
* [[Brescia Calcio|Brescia]]
* [[A.S. Cittadella|Cittadella]]
* [[Como 1907|Como]]
* [[Cosenza Calcio|Cosenza]]
* [[U.S. Cremonese|Cremonese]]
* [[F.C. Crotone|Crotone]]
* [[Frosinone Calcio|Frosinone]]
* [[U.S. Lecce|Lecce]]
* [[A.C. Monza|Monza]]
* [[Parma Calcio 1913|Parma]]
* [[A.C. Perugia Calcio|Perugia]]
* [[A.C. Pisa 1909|Pisa]]
* [[Pordenone Calcio|Pordenone]]
* [[Reggina 1914|Reggina]]
* [[S.P.A.L.|SPAL]]
* [[Ternana Calcio|Ternana]] 
* [[L.R. Vicenza Virtus|Vicenza]]
|
* [[U.S. Avellino 1912|Avellino]]
* [[U.S. Catanzaro 1929|Catanzaro]]
* [[Calcio Padova|Padova]]
* [[F.C. Südtirol|Südtirol]]
|}

== Format dan penempatan ==
Tim peserta memasuki kompetisi ini di berbagai tahap, di antaranya sebagai berikut:<ref name="format"/>
* '''Fase pertama''' (pertandingan satu leg)
** Babak pendahuluan: 4 tim dari [[Serie C]] dan 4 tim [[Serie B]] memulai turnamen
** Babak pertama: 4 tim pemenang dari babak pendahulan bergabung dengan 16 tim [[Serie B]] dan 12 tim dari [[Serie A]]
** Babak kedua: 16 tim pemenang dari babak sebelumnya saling berhadapan
* '''Fase kedua'''
** Babak 16 besar (satu leg): 8 tim pemenang dari babak sebelumnya bergabung dengan klub-klub Serie A, unggulan 1–8
** Perempat final (satu leg): 8 tim pemenang dari babak sebelumnya saling berhadapan
** Semifinal (dua leg): 4 tim pemenang dari babak sebelumnya saling berhadapan
** Final (satu leg): 2 tim pemenang dari babak sebelumnya saling berhadapan

== Jadwal ==
Jadwal setiap babak diumumkan pada 12 Juli 2021.<ref>{{Cite web|title=Comunicato Ufficiale n.2 - Date di calendario competizioni Serie A TIM stagione sportiva 2021/2022|url=https://www.legaseriea.it/uploads/default/attachments/comunicati/comunicati_m/8875/files/allegati/8974/2_-_date_di_calendario_serie_a_tim_2021-2022.pdf|access-date=21 Juli 2021|website=legaseriea.it|date=12 Juli 2021|language=it|archive-date=2021-07-12|archive-url=https://web.archive.org/web/20210712164626/https://www.legaseriea.it/uploads/default/attachments/comunicati/comunicati_m/8875/files/allegati/8974/2_-_date_di_calendario_serie_a_tim_2021-2022.pdf|dead-url=yes}}</ref>

{| class="wikitable" style="text-align: center; font-size: 100%; width: 800px;"
! width=11% | Fase
! width=15% | Babak
! width=10% | Klub yang tersisa
! width=10% | Klub yang terlibat
! width=10% | Dari babak sebelumnya
! width=10% | Klub yang masuk di babak ini
! width=16% | Leg pertama
! width=16% | Leg kedua
|-
| rowspan=3 align=center | Fase pertama
| align="center" | Babak pendahuluan
| align=center | 44
| align=center | 8
| align=center | tidak ada
| align=center | 8
| colspan=2 align=center | 7–8 Agustus 2021
|-
| align=center | Babak pertama
| align=center | 40
| align=center | 32
| align=center | 4
| align=center | 28
| colspan=2 align=center | 13–16 Agustus 2021
|-
| align=center | Babak kedua
| align=center | 24
| align=center | 16
| align=center | 16
| align=center | tidak ada
| colspan=2 align=center | 14–16 Desember 2021
|-
| rowspan=4 align=center | Fase final
| align=center | Babak 16 besar
| align=center | 16
| align=center | 16
| align=center | 8
| align=center | 8
| colspan=2 align=center | 12–19 Januari 2022
|-
| align=center | Perempat final
| align=center | 8
| align=center | 8
| align=center | 8
| align=center | tidak ada
| colspan=2 align=center | 9 Februari 2022
|-
| align=center | Semifinal
| align=center | 4
| align=center | 4
| align=center | 4
| align=center | tidak ada
| align=center | 2 Maret 2022
| align=center | 20 April 2022
|-
| align=center | Final
| align=center | 2
| align=center | 2
| align=center | 2
| align=center | tidak ada
| colspan=2 align=center | 11 Mei 2022
|}

== Babak pendahuluan ==
Sebanyak 8 tim dari [[Serie B]] dan [[Serie C]] berlaga di babak ini, 4 di antaranya melaju ke babak pertama. Tanggal dan waktu pertandingan dirilis pada 21 Juli 2021.<ref>{{Cite web|title=Comunicato Ufficiale n.11 - Coppa Italia 2021/2022 - Turno preliminare|url=https://www.legaseriea.it/uploads/default/attachments/comunicati/comunicati_m/8885/files/allegati/8984/11_-_turno_preliminare_coppa_italia_21-22.pdf|access-date=21 Juli 2021|website=legaseriea.it|date=21 Juli 2021|language=it|archive-date=2021-07-21|archive-url=https://web.archive.org/web/20210721125139/https://www.legaseriea.it/uploads/default/attachments/comunicati/comunicati_m/8885/files/allegati/8984/11_-_turno_preliminare_coppa_italia_21-22.pdf|dead-url=yes}}</ref>

{{Football box collapsible
|date = 7 Agustus 2021
|time = 19:00 [[Waktu Musim Panas Eropa Tengah|CEST]]
|team1 = '''[[Como 1907|Como]] (2)'''
|score = 2–2
|aet = yes
|report = https://id.soccerway.com/matches/2021/08/07/italy/coppa-italia/calcio-como/fc-catanzaro/3564574/
|team2 = [[U.S. Catanzaro 1929|Catanzaro]] (3)
|goals1 = 
* [[Moutir Chajia|Chajia]] {{goal|32||56}}
|goals2 = 
* [[Massimiliano Carlini|Carlini]] {{goal|51}}
* [[Luca Verna|Verna]] {{goal|88}}
|stadium = [[Stadion Silvio Piola (Novara)|Stadion Silvio Piola]]
|location = [[Novara]]
|attendance = 346
|referee = Matteo Marcenaro
|penalties1 = 
* [[Alessandro Gabrielloni|Gabrielloni]] {{pengoal}}
* [[Elvis Kabashi|Kabashi]] {{pengoal}}
* [[Lewis Walker (pemain sepak bola)|Walker]] {{pengoal}}
* [[Azzedine Dkidak|Dkidak]] {{penmiss}}
* [[Alessandro Bellemo|Bellemo]] {{penmiss}}
|penaltyscore = 3–4
|penalties2 =
* {{pengoal}} [[Massimiliano Carlini|Carlini]]
* {{pengoal}} [[Jari Vandeputte|Vandeputte]]
* {{penmiss}} [[Luca Verna|Verna]]
* {{pengoal}} [[Francesco Bombagi|Bombagi]]
* {{pengoal}} [[Federico Vázquez|Vázquez]]
}}
{{Football box collapsible
|id=Ternana v Avellino|date = 8 Agustus 2021
|time = 18:30 [[Waktu Musim Panas Eropa Tengah|CEST]]
|team1 = [[Ternana Calcio|Ternana]] (2)
|score = 1–1
|report =https://int.soccerway.com/matches/2021/08/08/italy/coppa-italia/ternana-calcio/us-avellino/3564572/ 
|team2 = '''[[U.S. Avellino 1912|Avellino]] (3)'''
|goals1 =*[[César Falletti|Falletti]] {{goal|62}} 
|goals2 =*[[Santo D'Angelo|D'Angelo]] {{goal|25}} 
|stadium = [[Stadion Libero Liberati]]
|aet=yes|location = [[Terni]]
|attendance = 1.498
|referee = Niccolò Baroni
|penalties1=*[[Fabrizio Paghera|Paghera]] {{penmiss}}
*[[Christian Capone|Capone]] {{penmiss}}
*[[Stefano Pettinari|Pettinari]] {{pengoal}}
*[[Simone Mazzocchi|Mazzocchi]] {{pengoal}}
*[[Aniello Salzano|Salzano]] {{pengoal}}
*[[Federico Furlan|Furlan]] {{pengoal}}|penaltyscore=4–3|penalties2=*{{pengoal}} [[Vincenzo Plescia|Plescia]]
*{{pengoal}} [[Salvatore Aloi|Aloi]]
*{{pengoal}} [[Fabio Tito|Tito]]
*{{penmiss}} [[Alberto De Francesco|De Francesco]]
*{{penmiss}} [[Riccardo Maniero|Maniero]]
*{{penmiss}} [[Agostino Rizzo|Rizzo]]}}
{{Football box collapsible
|id=Perugia v Südtirol|date = 8 Agustus 2021
|time = 19:00 [[Waktu Musim Panas Eropa Tengah|CEST]]
|team1 = [[A.C. Perugia Calcio|Perugia]] (2)
|score = 1–0
|report =https://int.soccerway.com/matches/2021/08/08/italy/coppa-italia/perugia-calcio/fc-sudtirol-bolzano/3564573/ 
|team2 = '''[[F.C. Südtirol|Südtirol]] (3)'''
|goals1 =*[[Mirko Carretta|Carretta]] {{goal|47}} 
|goals2 = 
|stadium = [[Stadion Renato Curi]]
|location = [[Perugia]]
|attendance = 1.100
|referee = Gianpiero Miele
}}
{{Football box collapsible
|id=Padova v Alessandria|date = 8 Agustus 2021
|time = 20:30 [[Waktu Musim Panas Eropa Tengah|CEST]]
|team1 = '''[[Calcio Padova|Padova]] (3)'''
|score = 0–2
|report =https://int.soccerway.com/matches/2021/08/08/italy/coppa-italia/biancoscudati-padova/us-alessandria-1912/3564571/ 
|team2 = [[U.S. Alessandria Calcio 1912|Alessandria]] (2)
|goals1 = 
|goals2 =*[[Simone Corazza|Corazza]] {{goal|102}}
*[[Francesco Orlando (pemain sepak bola)|Orlando]] {{goal|106}} 
|stadium = [[Stadion Euganeo]]
|aet=yes|location = [[Padova]]
|attendance = 401
|referee = Daniele Minelli
|note=
}}

== Babak pertama ==
Sebanyak 32 tim (4 tim pemenang dari babak pendahuluan, 16 tim dari [[Serie B]] dan 12 tim [[Serie A]], unggulan 9–20) bertanding pada babak ini, 16 tim pemenang melaju ke babak kedua.

{{Football box collapsible
|id=Pordenone v Spezia|date = 13 Agustus 2021
|time = 17:45 [[Waktu Musim Panas Eropa Tengah|CEST]]
|team1 = '''[[Pordenone Calcio|Pordenone]] (2)'''
|score = 1–3
|report = https://id.soccerway.com/matches/2021/08/13/italy/coppa-italia/pordenone-calcio-ssd/asd-spezia-calcio-2008/3564585/
|team2 = [[Spezia Calcio|Spezia]] (1) 
|goals1 = 
*[[Michael Folorunsho|Folorunsho]] {{goal|51|pen.}}
|goals2 = 
*[[Martin Erlić|Erlić]] {{goal|39}}
*[[Dimitris Nikolaou|Nikolaou]] {{goal|45+2}}
*[[Ebrima Colley|Colley]] {{goal|83|pen.}}
|stadium = [[Stadion Guido Teghil]]
|location = [[Lignano Sabbiadoro]]
|attendance = 600
|referee =Davide Ghersini 
}}
{{Football box collapsible
|id=Genoa v Perugia|date = 13 Agustus 2021
|time = 18:00 [[Waktu Musim Panas Eropa Tengah|CEST]]
|team1 = [[Genoa C.F.C.|Genoa]] (1)
|score = 3–2
|report = https://id.soccerway.com/matches/2021/08/13/italy/coppa-italia/genoa-cfc/perugia-calcio/3564583/
|team2 = '''[[A.C. Perugia Calcio|Perugia]] (2)'''
|goals1 = 
*[[Domenico Criscito|Criscito]] {{goal|26|pen.}}
*[[Leandro Chichizola|Chichizola]] {{goal|41|o.g.}}
*[[Yayah Kallon|Kallon]] {{goal|87}}
|goals2 = 
*[[Mirko Carretta|Carretta]] {{goal|2}}
*[[Francesco Lisi|Lisi]] {{goal|10}}
|stadium = [[Stadion Luigi Ferraris]]
|location = [[Genova]]
|attendance = 522
|referee =Antonio Rapuano 
}}
{{Football box collapsible
|id=Udinese v Ascoli|date = 13 Agustus 2021
|time = 20:45 [[Waktu Musim Panas Eropa Tengah|CEST]]
|team1 = [[Udinese Calcio|Udinese]] (1)
|score = 3–1
|report = https://id.soccerway.com/matches/2021/08/13/italy/coppa-italia/udinese-calcio/ascoli-calcio/3564579/
|team2 = '''[[Ascoli Calcio 1898 F.C.|Ascoli]] (2)'''
|goals1 = 
*[[Roberto Pereyra|Pereyra]] {{goal|11||55}}
*[[Nahuel Molina|Molina]] {{goal|53}}
|goals2 = 
*[[Tommaso D'Orazio|D'Orazio]] {{goal|90+2}}
|stadium = [[Dacia Arena]]
|location = [[Udine]]
|attendance = 2.604
|referee =Matteo Gariglio 
}}
{{Football box collapsible
|id=Fiorentina v Cosenza|date = 13 Agustus 2021
|time = 21:00 [[Waktu Musim Panas Eropa Tengah|CEST]]
|team1 = [[ACF Fiorentina|Fiorentina]] (1)
|score = 4–0
|report = https://id.soccerway.com/matches/2021/08/13/italy/coppa-italia/acf-fiorentina/cosenza-calcio-1914/3564587/
|team2 = '''[[Cosenza Calcio|Cosenza]] (2)'''
|goals1 =*[[Dušan Vlahović|Vlahović]] {{goal|4||45+4}}
*[[Nicolás González|González]] {{goal|37}}
*[[Lorenzo Venuti|Venuti]] {{goal|51}} 
|goals2 = 
|stadium = [[Stadion Artemio Franchi]]
|location = [[Firenze]]
|attendance = 3.600
|referee =Giacomo Camplone 
}}
{{Football box collapsible
|id=Benevento v Spal|date = 14 Agustus 2021
|time = 17:45 [[Waktu Musim Panas Eropa Tengah|CEST]]
|team1 = [[Benevento Calcio|Benevento]] (2)
|score = 2–1
|aet = yes
|report = https://id.soccerway.com/matches/2021/08/14/italy/coppa-italia/benevento-calcio/spal-1907/3564580/
|team2 = '''[[S.P.A.L.|SPAL]] (2)'''
|goals1 =*[[Riccardo Improta|Improta]] {{goal|32}}
*[[Gabriele Moncini|Moncini]] {{goal|120+4|pen.}} 
|goals2 =*[[Gabriele Moncini|Moncini]] {{goal|90+5|o.g.}} 
|stadium = [[Stadion Ciro Vigorito]]
|location = [[Benevento]]
|attendance =686 
|referee =Francesco Cosso 
}}
{{Football box collapsible
|id=Cittadella v Monza|date = 14 Agustus 2021
|time = 18:00 [[Waktu Musim Panas Eropa Tengah|CEST]]
|team1 = [[A.S. Cittadella|Cittadella]] (2)
|score = 2–1
|report = https://id.soccerway.com/matches/2021/08/14/italy/coppa-italia/as-cittadella/ac-monza-brianza-1912/3564578/
|team2 = '''[[A.C. Monza|Monza]] (2)'''
|goals1 =*[[Orji Okwonkwo|Okwonkwo]] {{goal|8}}
*[[Mamadou Tounkara|Tounkara]] {{goal|40}} 
|goals2 =*[[Carlos Augusto Zopolato Neves|Augusto]] {{goal|25}} 
|stadium = [[Stadion Pier Cesare Tombolato]]
|location = [[Cittadella]]
|attendance =530 
|referee =Antonio Di Martino 
}}
{{Football box collapsible
|id=Hellas Verona v Catanzaro|date = 14 Agustus 2021
|time = 20:45 [[Waktu Musim Panas Eropa Tengah|CEST]]
|team1 = [[Hellas Verona F.C.|Hellas Verona]] (1)
|score = 3–0
|report = https://id.soccerway.com/matches/2021/08/14/italy/coppa-italia/hellas-verona-fc/fc-catanzaro/3564590/
|team2 = '''[[U.S. Catanzaro 1929|Catanzaro]] (3)'''
|goals1 =*[[Koray Günter|Günter]] {{goal|23}} 
*[[Pasquale Fazio|Fazio]] {{goal|33|o.g.}} 
*[[Darko Lazović|Lazović]] {{goal|42}} 
|goals2 = 
|stadium = [[Stadion Marcantonio Bentegodi]]
|location = [[Verona]]
|attendance =1.784 
|referee =Luca Pairetto 
}}
{{Football box collapsible
|id=Cagliari v Pisa|date = 14 Agustus 2021
|time = 21:00 [[Waktu Musim Panas Eropa Tengah|CEST]]
|team1 = [[Cagliari Calcio|Cagliari]] (1)
|score = 3–1
|report = https://id.soccerway.com/matches/2021/08/14/italy/coppa-italia/cagliari-calcio/pisa-calcio/3564577/
|team2 = '''[[A.C. Pisa 1909|Pisa]] (2)'''
|goals1 =*[[Răzvan Marin|Marin]] {{goal|28}} 
*[[Antonio Caracciolo|Caracciolo]] {{goal|37|o.g.}} 
*[[Alessandro Deiola|Deiola]] {{goal|45+3}} 
|goals2 =*[[Gaetano Masucci|Masucci]] {{goal|67}}  
|stadium = [[Sardegna Arena]]
|location = [[Cagliari]]
|attendance =2.620 
|referee =Gianluca Manganiello 
}}
{{Football box collapsible
|id=Empoli v Vicenza|date = 15 Agustus 2021
|time = 17:45 [[Waktu Musim Panas Eropa Tengah|CEST]]
|team1 = [[Empoli F.C.|Empoli]] (1)
|score = 4–2
|report = https://id.soccerway.com/matches/2021/08/15/italy/coppa-italia/empoli-fc/vicenza-calcio/3564589/
|team2 = '''[[L.R. Vicenza Virtus|Vicenza]] (2)'''
|goals1 =*[[Nedim Bajrami|Bajrami]] {{goal|11}} 
*[[Nicolas Haas|Haas]] {{goal|30}} 
*[[Leonardo Mancuso|Mancuso]] {{goal|37}} 
*[[Giovanni Crociata|Crociata]] {{goal|87}} 
|goals2 =*[[Nicola Dalmonte|Dalmonte]] {{goal|39}} 
*[[Davide Lanzafame|Lanzafame]] {{goal|56}}  
|stadium = [[Stadion Carlo Castellani]]
|location = [[Empoli]]
|attendance =0 
|referee =Juan Luca Sacchi 
}}
{{Football box collapsible
|id=Parma v Lecce|date = 15 Agustus 2021
|time = 18:00 [[Waktu Musim Panas Eropa Tengah|CEST]]
|team1 = '''[[Parma Calcio 1913|Parma]] (2)'''
|score = 1–3
|report = https://id.soccerway.com/matches/2021/08/15/italy/coppa-italia/parma-fc/us-lecce/3564588/
|team2 = [[U.S. Lecce|Lecce]] (2)
|goals1 =*[[Juan Brunetta (pemain sepak bola)|Brunetta]] {{goal|7}} 
|goals2 =*[[Massimo Coda|Coda]] {{goal|9||76}} 
*[[Alessandro Tuia|Tuia]] {{goal|40}} 
|stadium = [[Stadion Ennio Tardini]]
|location = [[Parma]]
|attendance =1.306 
|referee =Marco Serra 
}}
{{Football box collapsible
|id=Venezia v Frosinone|date = 15 Agustus 2021
|time = 20:45 [[Waktu Musim Panas Eropa Tengah|CEST]]
|team1 = [[Venezia F.C.|Venezia]] (1)
|score = 1–1
|report = https://id.soccerway.com/matches/2021/08/15/italy/coppa-italia/ssc-venezia/frosinone-calcio/3564581/
|team2 = '''[[Frosinone Calcio|Frosinone]] (2)'''
|goals1 =*[[Francesco Di Mariano|Di Mariano]] {{goal|101|pen.}} 
|goals2 =*[[Mirko Gori|Gori]] {{goal|93}} 
|stadium = [[Stadion Paolo Mazza]]
|aet=yes|location = [[Ferrara]]
|attendance =250 
|referee =Alessandro Prontrera 
|penalties1=*[[Arnór Sigurðsson|Sigurðsson]] {{pengoal}}
*[[Daan Heymans|Heymans]] {{pengoal}}
*[[Francesco Di Mariano|Di Mariano]] {{pengoal}}
*[[Tanner Tessmann|Tessmann]] {{penmiss}}
*[[Antonio Vacca|Vacca]] {{pengoal}}
*[[Pietro Ceccaroni|Ceccaroni]] {{pengoal}}
*[[Dennis Johnsen|Johnses]] {{pengoal}}
*[[Mattia Caldara|Caldara]] {{pengoal}}
*[[Tyronne Ebuehi|Ebuehi]] {{pengoal}}|penaltyscore=8–7|penalties2=*{{pengoal}} [[Camillo Ciano|Ciano]]
*{{penmiss}} [[Raffaele Maiello|Maiello]]
*{{pengoal}} [[Francesco Zampano|Zampano]]
*{{pengoal}} [[Pietro Iemmello|Iemmello]]
*{{pengoal}} [[Mattia Vitale|Vitale]]
*{{pengoal}} [[Nicolò Brighenti|Brighenti]]
*{{pengoal}} [[Przemysław Szymiński|Szymiński]]
*{{pengoal}} [[Alessio Zerbin|Zerbin]]
*{{penmiss}} [[Federico Gatti|Gatti]]}}
{{Football box collapsible
|id=Torino v Cremonese|date = 15 Agustus 2021
|time = 21:00 [[Waktu Musim Panas Eropa Tengah|CEST]]
|team1 = [[Torino F.C.|Torino]] (1)
|score = 0–0
|report = https://id.soccerway.com/matches/2021/08/15/italy/coppa-italia/torino-fc/us-cremonese/3564576/
|team2 = '''[[U.S. Cremonese|Cremonese]] (2)'''
|goals1 = 
|goals2 = 
|stadium = [[Stadion Olimpiade Grande Torino]]
|aet=yes|location = [[Turin]]
|attendance =1.484 
|referee =Giovanni Ayroldi 
|penalties1=*[[Rolando Mandragora|Mandragora]] {{pengoal}}
*[[Simone Verdi|Verdi]] {{pengoal}}
*[[Nicola Rauti|Rauti]] {{pengoal}}
*[[Ola Aina|Aina]] {{pengoal}}|penaltyscore=4–1|penalties2=*{{penmiss}} [[Daniel Ciofani|Ciofani]] 
*{{pengoal}} [[Luca Vido|Vido]] 
*{{penmiss}} [[Michele Castagnetti|Castagnetti]]}}
{{Football box collapsible
|id=Crotone v Brescia|date = 16 Agustus 2021
|time = 17:45 [[Waktu Musim Panas Eropa Tengah|CEST]]
|team1 = [[F.C. Crotone|Crotone]] (2)
|score = 2–2
|report = https://id.soccerway.com/matches/2021/08/16/italy/coppa-italia/fc-crotone/brescia-calcio/3564586/
|team2 = '''[[Brescia Calcio|Brescia]] (2)'''
|goals1 =*[[Miloš Vulić|Vulić]] {{goal|26}}
*[[Samuele Mulattieri|Mulattieri]] {{goal|76}} 
|goals2 =*[[Tom van de Looi|Van de Loi]] {{goal|46}}
*[[Riad Bajić|Bajić]] {{goal|67}} 
|stadium = [[Stadion Ezio Scida]]
|aet=yes|location = [[Crotone]]
|attendance =1.500 
|referee =Luca Massimi 
|penalties1=*[[Salvatore Molina|Molina]] {{pengoal}}
*[[Ahmad Benali|Benali]] {{pengoal}}
*[[Vasile Mogoș|Mogoș]] {{pengoal}}
*[[Miloš Vulić|Vulić]] {{pengoal}}|penaltyscore=4–2|penalties2=*{{pengoal}} [[Riad Bajić|Bajić]] 
*{{penmiss}} [[Stefano Moreo|Moreo]] 
*{{penmiss}} [[Emanuele Ndoj|Ndoj]] 
*{{pengoal}} [[Nikolas Spalek|Spalek]]}}
{{Football box collapsible
|id=Bologna v Ternana|date = 16 Agustus 2021
|time = 18:00 [[Waktu Musim Panas Eropa Tengah|CEST]]
|team1 = '''[[Bologna F.C. 1909|Bologna]] (1)'''
|score = 4–5
|report = https://id.soccerway.com/matches/2021/08/16/italy/coppa-italia/bologna-fc-1909/ternana-calcio/3564582/
|team2 = [[Ternana Calcio|Ternana]] (2)
|goals1 =*[[Nicolás Domínguez|Domínguez]] {{goal|38}}
*[[Marko Arnautović|Arnautović]] {{goal|56}}
*[[Roberto Soriano|Soriano]] {{goal|58}}
*[[Riccardo Orsolini|Orsolini]] {{goal|76|pen.}} 
|goals2 =*[[Davide Agazzi|Agazzi]] {{goal|6}}
*[[Alfredo Donnarumma|Donnarumma]] {{goal|21}}
*[[Diego Peralta (pemain sepak bola Argentina)|Peralta]] {{goal|40||54}}
*[[César Falletti|Falletti]] {{goal|50|pen.}} 
|stadium = [[Stadion Renato Dall'Ara]]
|location = [[Bologna]]
|attendance =5.360 
|referee =Luca Zufferli 
}}
{{Football box collapsible
|id=Salernitana v Reggina|date = 16 Agustus 2021
|time = 20:45 [[Waktu Musim Panas Eropa Tengah|CEST]]
|team1 = [[U.S. Salernitana 1919|Salernitana]] (1)
|score = 2–0
|report = https://id.soccerway.com/matches/2021/08/16/italy/coppa-italia/salernitana-calcio-1919/reggina-calcio/3564584/
|team2 = '''[[Reggina 1914|Reggina]] (2)'''
|goals1 =*[[Federico Bonazzoli|Bonazzoli]] {{goal|45+2||52}} 
|goals2 = 
|stadium = [[Stadion Arechi]]
|location = [[Salerno]]
|attendance =2.476 
|referee =Francesco Fourneau 
}}
{{Football box collapsible
|id=Sampdoria v Alessandria|date = 16 Agustus 2021
|time = 21:00 [[Waktu Musim Panas Eropa Tengah|CEST]]
|team1 = [[U.C. Sampdoria|Sampdoria]] (1)
|score = 3–2
|report = https://id.soccerway.com/matches/2021/08/16/italy/coppa-italia/uc-sampdoria/us-alessandria-1912/3564575/
|team2 = '''[[U.S. Alessandria Calcio 1912|Alessandria]] (2)'''
|goals1 =*[[Fabio Quagliarella|Quagliarella]] {{goal|28}}
*[[Manolo Gabbiadini|Gabbiadini]] {{goal|47}}
*[[Morten Thorsby|Thorsby]] {{goal|52}} 
|goals2 =*[[Riccardo Chiarello|Chiarello]] {{goal|8}}
*[[Simone Corazza|Corazza]] {{goal|45|pen.}} 
|stadium = [[Stadion Luigi Ferraris]]
|location = [[Genova]]
|attendance =1.249 
|referee =Andrea Colombo 
}}

== Babak kedua ==
16 tim pemenang dari babak pertama bertanding di babak kedua, 8 tim pemenang melaju ke babak 16 besar.

{{Football box collapsible
|id=Venezia v Ternana|date={{Tanggal-mulai|2021|12|14}}
|time = 15:00 [[Waktu Eropa Tengah|CET]]
|team1 = [[Venezia F.C.|Venezia]] (1)
|score = 3–1
|report = https://id.soccerway.com/matches/2021/12/15/italy/coppa-italia/ssc-venezia/ternana-calcio/3564601/
|team2 = '''[[Ternana Calcio|Ternana]] (2)'''
|goals1 = 
*[[Daan Heymans|Heymans]] {{goal|49}}
*[[Domen Črnigoj|Črnigoj]] {{goal|66}}
*[[Francesco Forte (pemain sepak bola kelahiran 1993)|Forte]] {{goal|81}}
|goals2 = 
*[[Stefano Pettinari|Pettinari]] {{goal|53}}
|stadium = [[Stadion Paolo Mazza]] 
|location = [[Ferrara]] 
|attendance =  5.219
|referee = Daniele Minelli
}}
{{Football box collapsible
|id=Udinese v Crotone|date={{Tanggal-mulai|2021|12|14}}
|time = 18:00 [[Waktu Eropa Tengah|CET]]
|team1 = [[Udinese Calcio|Udinese]] (1)
|score = 4–0
|report = https://id.soccerway.com/matches/2021/12/15/italy/coppa-italia/udinese-calcio/fc-crotone/3564603/
|team2 = '''[[F.C. Crotone|Crotone]] (2)'''
|goals1 = 
*[[Ignacio Pussetto|Pussetto]] {{goal|20||62}}
*[[Sebastien De Maio|De Maio]] {{goal|28}}
*[[Isaac Success|Success]] {{goal|41|pen.}}
|goals2 = 
|stadium = [[Dacia Arena]] 
|location = [[Udine]] 
|attendance = 1.291
|referee = Matteo Gualtieri
}}
{{Football box collapsible
|id=Genoa v Salernitana|date={{Tanggal-mulai|2021|12|14}}
|time = 21:00 [[Waktu Eropa Tengah|CET]]
|team1 = [[Genoa C.F.C.|Genoa]] (1)
|score = 1–0
|report = https://id.soccerway.com/matches/2021/12/15/italy/coppa-italia/genoa-cfc/salernitana-calcio-1919/3564602/
|team2 = '''[[U.S. Salernitana 1919|Salernitana]] (1)'''
|goals1 = 
*[[Caleb Ekuban|Ekuban]] {{goal|76}}
|goals2 = 
|stadium = [[Stadion Luigi Ferraris]] 
|location = [[Genova]] 
|attendance = 
|referee = Marco Serra
}}
{{Football box collapsible
|id=Hellas Verona v Empoli|date={{Tanggal-mulai|2021|12|15}}
|time = 15:00 [[Waktu Eropa Tengah|CET]]
|team1 = '''[[Hellas Verona F.C.|Hellas Verona]] (1)''' 
|score = 3–4
|report = https://id.soccerway.com/matches/2021/12/15/italy/coppa-italia/hellas-verona-fc/empoli-fc/3564605/
|team2 = [[Empoli F.C.|Empoli]] (1)
|goals1 = 
*[[Matteo Cancellieri|Cancellieri]] {{goal|18}}
*[[Ivan Ilić (pemain sepak bola kelahiran 2001)|Ilić]] {{goal|86}}
*[[Antonino Ragusa|Ragusa]] {{goal|88}}
|goals2 = 
*[[Andrea La Mantia|La Mantia]] {{goal|15}}
*[[Leonardo Mancuso|Mancuso]] {{goal|66|pen.|70}}
*[[Nedim Bajrami|Bajrami]] {{goal|74}}
|stadium = [[Stadion Marcantonio Bentegodi]] 
|location = [[Verona]]
|attendance = 1.101
|referee = Federico Dionisi
}}
{{Football box collapsible
|id=Cagliari v Cittadella|date={{Tanggal-mulai|2021|12|15}}
|time = 18:00 [[Waktu Eropa Tengah|CET]] 
|team1 = [[Cagliari Calcio|Cagliari]] (1)
|score = 3–1
|report = https://id.soccerway.com/matches/2021/12/15/italy/coppa-italia/cagliari-calcio/as-cittadella/3564599/
|team2 = '''[[A.S. Cittadella|Cittadella]] (2)'''
|goals1 = 
*[[Alessandro Deiola|Deiola]] {{goal|16}}
*[[Damir Ceter|Ceter]] {{goal|40}}
*[[Gastón Pereiro|Pereiro]] {{goal|64}}
|goals2 = 
*[[Daniele Donnarumma|Donnarumma]] {{goal|85}}
|stadium = [[Sardegna Arena]]
|location = [[Cagliari]]
|attendance = 2.797
|referee = Maria Ferrieri
}}
{{Football box collapsible
|id=Fiorentina v Benevento|date={{Tanggal-mulai|2021|12|15}}
|time = 21:00 [[Waktu Eropa Tengah|CET]] 
|team1 = [[ACF Fiorentina|Fiorentina]] (1)
|score = 2–1
|report = https://id.soccerway.com/matches/2021/12/15/italy/coppa-italia/acf-fiorentina/benevento-calcio/3564600/
|team2 = '''[[Benevento Calcio|Benevento]] (2)'''
|goals1 = 
*[[Nikola Milenković|Milenković]] {{goal|19}}
*[[Riccardo Sottil|Sottil]] {{goal|47}}
|goals2 = 
*[[Gabriele Moncini|Moncini]] {{goal|51}}
|stadium = [[Stadion Artemio Franchi]] 
|location = [[Firenze]] 
|attendance = 13.800
|referee = Luca Zufferli
}}
{{Football box collapsible
|id=Spezia v Lecce|date={{Tanggal-mulai|2021|12|16}}
|time = 18:00 [[Waktu Eropa Tengah|CET]] 
|team1 = '''[[Spezia Calcio|Spezia]] (1)'''
|score = 0–2
|report = https://id.soccerway.com/matches/2021/12/15/italy/coppa-italia/asd-spezia-calcio-2008/us-lecce/3564604/
|team2 = [[U.S. Lecce|Lecce]] (2)
|goals1 = 
|goals2 = 
*[[Marcin Listkowski|Listkowski]] {{goal|43}}
*[[Arturo Calabresi|Calabresi]] {{goal|55}}
|stadium = [[Stadion Dino Manuzzi]] 
|location = [[Cesena]] 
|attendance = 
|referee = Valerio Marini
}}
{{Football box collapsible
|id=Sampdoria v Torino|date={{Tanggal-mulai|2021|12|16}}
|time = 18:00 [[Waktu Eropa Tengah|CET]] 
|team1 = [[U.C. Sampdoria|Sampdoria]] (1)
|score = 2–1
|report = https://id.soccerway.com/matches/2021/12/15/italy/coppa-italia/uc-sampdoria/torino-fc/3564598/
|team2 = '''[[Torino F.C.|Torino]] (1)'''
|goals1 = 
*[[Fabio Quagliarella|Quagliarella]] {{goal|16|pen.}}
*[[Valerio Verre|Verre]] {{goal|60}}
|goals2 = [[Rolando Mandragora|Mandragora]] {{goal|54|pen.}}
|stadium = [[Stadion Luigi Ferraris]] 
|location = [[Genova]] 
|attendance = 3,124
|referee = Marco Piccinini
}}

== Peta perjalanan menuju final ==
{{#invoke:RoundN|main|columns=4|score-boxes=2+sum
|style=font-size:90%; white-space:nowrap
|3rdplace=no|short_brackets=
|score-width=27|team-width=125
|RD1=[[#Babak 16 besar|Babak 16 besar]]
|RD2=[[#Perempat final|Perempat final]]
|RD3=[[#Semifinal|Semifinal]]
|RD4=[[#Final|Final]]
<!-- Babak 16 besar -->
||[[Juventus F.C.|Juventus]]        |4||[[U.C. Sampdoria|Sampdoria]]  |1|
||[[U.S. Sassuolo Calcio|Sassuolo]] |1||[[Cagliari Calcio|Cagliari]]  |0|
||[[Atalanta B.C.|Atalanta]]        |2||[[Venezia F.C.|Venezia]]  |0|
||[[S.S.C. Napoli|Napoli]]          |2|| [[ACF Fiorentina|Fiorentina]] {{aet}} |5|
||[[A.C. Milan|Milan]] {{aet}}      |3||[[Genoa C.F.C|Genoa]]  |1|
||[[S.S. Lazio|Lazio]] {{aet}}      |1||[[Udinese Calcio|Udinese]]  |0|
||[[Inter Milan|Internazionale]] {{aet}}  |3||[[Empoli F.C.|Empoli]]  |2|
||[[A.S. Roma|Roma]]                |3||[[U.S. Lecce|Lecce]]  |1|

<!-- Perempat final -->
||[[Juventus F.C.|Juventus]] |2||[[U.S. Sassuolo Calcio|Sassuolo]] |1|
||[[Atalanta B.C.|Atalanta]] |2||[[ACF Fiorentina|Fiorentina]] |3|
||[[A.C. Milan|Milan]] |4||[[S.S. Lazio|Lazio]] |0|
||[[Inter Milan|Internazionale]] |2||[[A.S. Roma|Roma]] |0|

<!-- Semifinal -->
||[[Juventus F.C.|Juventus]]|1|2|[[ACF Fiorentina|Fiorentina]]|0|0
||[[A.C. Milan|Milan]]|0|0|[[Inter Milan|Internazionale]]|0|3
<!-- Final -->
||[[Juventus F.C.|Juventus]]|2||[[Inter Milan|Internazionale]] {{aet}}|4|
}}

== Babak 16 besar ==
Pertandingan babak 16 besar dimainkan oleh delapan tim pemenang dari babak kedua dan klub unggulan 1–8 di [[Serie A 2020–2021]].

Lecce satu-satunya tim [[Serie B]] pada babak 16 besar.

{{Football box collapsible
|date={{Tanggal-mulai|2022|1|12}}
|time = 17:30 [[Waktu Eropa Tengah|CET]]
|team1 = [[Atalanta B.C.|Atalanta]] (1)
|score = 2–0
|report = https://www.legaseriea.it/en/coppa-italia/match-report/2021-22/OTTAV/UNI/1/ATAVEN
|team2 = '''[[Venezia F.C.|Venezia]] (1)'''
|goals1 = 
*[[Luis Muriel|Muriel]] {{goal|12}}
*[[Joakim Mæhle|Mæhle]] {{goal|88}}
|goals2 = 
|stadium = [[Gewiss Stadium]]
|location = [[Bergamo]]
|attendance = 
|referee = Ivano Pezzuto
}}
{{Football box collapsible
|date={{Tanggal-mulai|2022|1|13}}
|time = 18:00 [[Waktu Eropa Tengah|CET]]
|team1 = '''[[S.S.C. Napoli|Napoli]] (1)'''
|score = 2–5
|aet = yes
|report = https://www.legaseriea.it/en/coppa-italia/match-report/2021-22/OTTAV/UNI/1/NAPFIO
|team2 = [[ACF Fiorentina|Fiorentina]] (1)
|goals1 = 
*[[Dries Mertens|Mertens]] {{goal|44}}
*[[Andrea Petagna|Petagna]] {{goal|90+5}}
|goals2 = 
*[[Dušan Vlahović|Vlahović]] {{goal|41}}
*[[Cristiano Biraghi|Biraghi]] {{goal|57}}
*[[Lorenzo Venuti|Venuti]] {{goal|105+1}}
*[[Krzysztof Piątek|Piątek]] {{goal|108}}
*[[Youssef Maleh|Maleh]] {{goal|119}}
|stadium = [[Stadio Diego Armando Maradona]]
|location = [[Naples]]
|attendance = 
|referee = Giovanni Ayroldi
}}
{{Football box collapsible
|date={{Tanggal-mulai|2022|1|13}}
|time = 21:00 [[Waktu Eropa Tengah|CET]]
|team1 = [[A.C. Milan|Milan]] (1)
|score = 3–1
|aet = yes
|report = https://www.legaseriea.it/en/coppa-italia/match-report/2021-22/OTTAV/UNI/1/MILGEN
|team2 = '''[[Genoa C.F.C.|Genoa]] (1)'''
|goals1 = 
*[[Olivier Giroud|Giroud]] {{goal|74}}
*[[Rafael Leão|Leão]] {{goal|102}}
*[[Alexis Saelemaekers|Saelemaekers]] {{goal|112}}
|goals2 = 
*[[Leo Skiri Østigård|Østigård]] {{goal|17}}
|stadium = [[San Siro]]
|location = [[Milan]]
|attendance = 
|referee = Gianluca Aureliano
}}
{{Football box collapsible
|date={{Tanggal-mulai|2022|1|18}}
|time = 17:30 [[Waktu Eropa Tengah|CET]]
|team1 = [[S.S. Lazio|Lazio]] (1)
|score = 1–0
|aet = yes
|report = https://www.legaseriea.it/en/coppa-italia/match-report/2021-22/OTTAV/UNI/1/LAZUDI
|team2 = '''[[Udinese Calcio|Udinese]] (1)'''
|goals1 = 
*[[Ciro Immobile|Immobile]] {{goal|106}}
|goals2 = 
|stadium = [[Stadion Olimpiade (Roma)|Stadion Olimpico]]
|location = [[Roma]]
|attendance = 
|referee = Daniele Minelli
}}
{{Football box collapsible
|date={{Tanggal-mulai|2022|1|18}}
|time = 21:00 [[Waktu Eropa Tengah|CET]]
|team1 = [[Juventus F.C.|Juventus]] (1)
|score = 4–1
|report = https://www.legaseriea.it/en/coppa-italia/match-report/2021-22/OTTAV/UNI/1/JUVSAM
|team2 = '''[[U.C. Sampdoria|Sampdoria]] (1)'''
|goals1 = 
*[[Juan Cuadrado|Cuadrado]] {{goal|25}}
*[[Daniele Rugani|Rugani]] {{goal|52}}
*[[Paulo Dybala|Dybala]] {{goal|67}}
*[[Álvaro Morata|Morata]] {{goal|77|pen.}}
|goals2 = 
*[[Andrea Conti (pemain sepak bola kelahiran 1994)|Conti]] {{goal|63}}
|stadium = [[Stadion Juventus]]
|location = [[Turin]]
|attendance = 
|referee = Francesco Fourneau
}}
{{Football box collapsible
|date={{Tanggal-mulai|2022|1|19}}
|time = 17:30 [[Waktu Eropa Tengah|CET]]
|team1 = [[U.S. Sassuolo Calcio|Sassuolo]] (1)
|score = 1–0
|report = https://www.legaseriea.it/en/coppa-italia/match-report/2021-22/OTTAV/UNI/1/SASCAG
|team2 = '''[[Cagliari Calcio|Cagliari]] (1)'''
|goals1 = 
*[[Abdou Harroui|Harroui]] {{goal|18}}
|goals2 = 
|stadium = [[Mapei Stadium – Città del Tricolore]]
|location = [[Reggio Emilia]]
|attendance = 
|referee = Matteo Marchetti
}}
{{Football box collapsible
|date={{Tanggal-mulai|2022|1|19}}
|time = 21:00 [[Waktu Eropa Tengah|CET]]
|team1 = [[Inter Milan|Internazionale]] (1)
|score = 3–2
|aet = yes
|report = https://www.legaseriea.it/en/coppa-italia/match-report/2021-22/OTTAV/UNI/1/INTEMP
|team2 = '''[[Empoli F.C.|Empoli]] (1)'''
|goals1 = 
*[[Alexis Sánchez|Sánchez]] {{goal|13}}
*[[Andrea Ranocchia|Ranocchia]] {{goal|90+1}}
*[[Stefano Sensi|Sensi]] {{goal|104}}
|goals2 = 
*[[Nedim Bajrami|Bajrami]] {{goal|61}}
*[[Ionuț Radu|Radu]] {{goal|76|o.g.}}
|stadium = [[San Siro]]
|location = [[Milan]]
|attendance = 
|referee = Juan Luca Sacchi
}}
{{Football box collapsible
|date={{Tanggal-mulai|2022|1|20}}
|time = 21:00 [[Waktu Eropa Tengah|CET]]
|team1 = [[A.S. Roma|Roma]] (1)
|score = 3–1
|report = https://www.legaseriea.it/en/coppa-italia/match-report/2021-22/OTTAV/UNI/1/ROMLEC
|team2 = '''[[U.S. Lecce|Lecce]] (2)'''
|goals1 = 
*[[Marash Kumbulla|Kumbulla]] {{goal|40}}
*[[Tammy Abraham|Abraham]] {{goal|54}}
*[[Eldor Shomurodov|Shomurodov]] {{goal|81}}
|goals2 = 
*[[Arturo Calabresi|Calabresi]] {{goal|14}}
|stadium = [[Stadion Olimpiade (Roma)|Stadion Olimpico]]
|location = [[Roma]]
|attendance = 
|referee = Manuel Volpi
}}

== Perempat final ==
Pertandingan perempat final akan dimainkan oleh delapan tim pemenang babak 16 besar pada 8–10 Februari 2022.

{{Football box collapsible
|date = {{Tanggal-mulai|2022|2|8}}
|time = 21:00 [[Waktu Eropa Tengah|CET]]
|team1 = [[Inter Milan|Internazionale]] (1)
|team2 = '''[[A.S. Roma|Roma]] (1)'''
|score = 2–0
|report = https://www.legaseriea.it/en/coppa-italia/match-report/2021-22/QUART/UNI/1/INTROM
|goals1 =
* [[Edin Džeko|Džeko]] {{goal|1}}
* [[Alexis Sánchez|Sánchez]] {{goal|68}}
|goals2 = 
|stadium = [[San Siro]]
|location = [[Milan]]
|attendance = 
|referee = [[Marco Di Bello]]
}}
{{Football box collapsible
|date = {{Tanggal-mulai|2022|2|9}}
|time = 21:00 [[Waktu Eropa Tengah|CET]]
|team1 = [[A.C. Milan|Milan]] (1)
|team2 = '''[[S.S. Lazio|Lazio]] (1)'''
|score = 4–0
|report = https://www.legaseriea.it/en/coppa-italia/match-report/2021-22/QUART/UNI/1/MILLAZ
|goals1 = 
* [[Rafael Leão|Leão]] {{goal|24}}
* [[Olivier Giroud|Giroud]] {{goal|41||45+1}}
* [[Franck Kessié|Kessié]] {{goal|79}}
|goals2 = 
|stadium = [[San Siro]]
|location = [[Milan]]
|attendance = 
|referee = Simone Sozza
}}
{{Football box collapsible
|date = {{Tanggal-mulai|2022|2|10}}
|time = 18:00 [[Waktu Eropa Tengah|CET]]
|team1 =  '''[[Atalanta B.C.|Atalanta]] (1)'''
|team2 = [[ACF Fiorentina|Fiorentina]] (1)
|report = https://www.legaseriea.it/en/coppa-italia/match-report/2021-22/QUART/UNI/1/ATAFIO
|score = 2–3
|goals1 = 
* [[Davide Zappacosta|Zappacosta]] {{goal|30}}
* [[Jeremie Boga|Boga]] {{goal|56}}
|goals2 = 
* [[Krzysztof Piątek|Piątek]] {{goal|9|pen.|71}}
* [[Nikola Milenković|Milenković]] {{goal|90+4}}
|stadium = [[Stadion Atleti Azzurri d'Italia|Atleti Azzurri d'Italia]]
|location = [[Bergamo]]
|attendance = 
|referee = Michael Fabbri
}}
{{Football box collapsible
|date = {{Tanggal-mulai|2022|2|10}}
|time = 21:00 [[Waktu Eropa Tengah|CET]]
|team1 = [[Juventus F.C.|Juventus]] (1)
|team2 = '''[[U.S. Sassuolo Calcio|Sassuolo]] (1)'''
|report = https://www.legaseriea.it/en/coppa-italia/match-report/2021-22/QUART/UNI/1/JUVSAS
|score = 2–1
|goals1 = 
* [[Paulo Dybala|Dybala]] {{goal|3}}
* [[Ruan Tressoldi|Tressoldi]] {{goal|88|b.d.}}
|goals2 = 
* [[Hamed Junior Traorè|Traorè]] {{goal|24}}
|stadium = [[Stadion Juventus]]
|location = [[Turin]]
|attendance = 
|referee = Livio Marinelli
}}

==Semifinal==
=== Pertandingan pertama ===
{{Football box collapsible
|date = {{Tanggal-mulai|2022|3|1}}
|time = 21:00 [[Waktu Eropa Tengah|CET]]
|team1 = [[A.C. Milan|AC Milan]] (1)
|team2 = [[FC Internazionale Milano|Inter Milan]] (1)
|score = 0–0
|report = https://www.legaseriea.it/en/coppa-italia/match-report/2021-22/SEMIF/AND/1/MILINT
|goals1 = 
|goals2 = 
|stadium = [[San Siro]]
|location = [[Milan]]
|attendance = 53.881
|referee = 
}}
{{Football box collapsible
|date = {{Tanggal-mulai|2022|3|2}}
|time = 21:00 [[Waktu Eropa Tengah|CET]]
|team1 = [[ACF Fiorentina|Fiorentina]] (1)
|team2 = [[Juventus F.C.|Juventus]] (1)
|score = 0–1
|report = https://www.legaseriea.it/en/coppa-italia/match-report/2021-22/SEMIF/AND/1/FIOJUV
|goals1 = 
|goals2 = 
*[[Lorenzo Venuti|Venuti]] {{goal|90+2|o.g.}}
|stadium = [[Stadion Artemio Franchi]]
|location = [[Firenze]]
|attendance = 28.039
|referee = [[Marco Guida]]
}}

=== Pertandingan kedua ===
{{Football box collapsible
|date = {{Tanggal-mulai|2022|4|19}}
|time = 21:00 [[Waktu Musim Panas Eropa Tengah|CEST]]
|team1 = [[FC Internazionale Milano|Inter Milan]] (1)
|team2 = '''[[A.C. Milan|AC Milan]]''' (1)
|score = 3–0
|aggregatescore = 3–0
|report = https://www.legaseriea.it/en/coppa-italia/match-report/2021-22/SEMIF/RIT/1/INTMIL
|goals1 = 
*[[Lautaro Martínez|Martínez]] {{goal|4||40}}
*[[Robin Gosens|Gosens]] {{goal|82}}
|goals2 = 
|stadium = [[San Siro]]
|location = [[Milan]]
|attendance = 74.508
|referee = Maurizio Mariani
}}
{{Football box collapsible
|date = {{Tanggal-mulai|2022|4|20}}
|time = 21:00 [[Waktu Musim Panas Eropa Tengah|CEST]] 
|team1 = [[Juventus F.C.|Juventus]] (1) 
|team2 = '''[[ACF Fiorentina|Fiorentina]]''' (1)
|score = 2–0
|aggregatescore = 3–0
|report = 
|goals1 = 
*[[Federico Bernardeschi|Bernardeschi]] {{goal|32}}
*[[Danilo Luiz da Silva|Danilo]] {{goal|90+4}}
|goals2 = 
|stadium = [[Stadion Juventus]]
|location = [[Turin]]
|attendance = 32.109
|referee = Daniele Doveri
}}

==Final==
<!--{{main article|Final Piala Italia 2022}}-->
{{Footballbox
|date = {{Tanggal-mulai|2022|5|11}}
|time = 
|team1 = Juventus
|score = 2 v 4
|report = 
|team2 = Inter Milan
|goals1 = 
|goals2 = 
|stadium = [[Stadion Olimpiade (Roma)|Stadion Olimpico]], Roma
|attendance = 
|referee = 
}}

== Pencetak gol terbanyak ==
<!--{{Update|part=Section|date=August 2021}}-->{{Updated|9 Februari 2022<ref>{{cite web|url=https://id.soccerway.com/national/italy/coppa-italia/20212022/1st-round/r63964/players/|title=Players - Coppa Italia|website=Soccerway}}</ref>}}
{| class="wikitable sortable" style="text-align:center" width="400px"
!Peringkat
!Pemain
!Klub
!Gol
|-
|rowspan="4"|1
|align="left"|{{flagicon|ALB}} [[Nedim Bajrami]]
|align="left"|Empoli
|rowspan="4"|3
|-
|align="left"|{{flagicon|FRA}} [[Olivier Giroud]]
|align="left"|Milan
|-
|align="left"|{{flagicon|ITA}} [[Leonardo Mancuso]]
|align="left"|Empoli
|-
|align="left"|{{flagicon|SRB}} [[Dušan Vlahović]]
|align="left"|Fiorentina
|-
|rowspan="16"|5
|align="left"|{{flagicon|ITA}} [[Federico Bonazzoli]]
|align="left"|Salernitana
|rowspan="16"|2
|-
|align="left"|{{flagicon|ITA}} [[Arturo Calabresi]]
|rowspan="2" align="left"|Lecce
|-
|align="left"|{{flagicon|ITA}} [[Massimo Coda]]
|-
|align="left"|{{flagicon|ITA}} [[Mirko Carretta]]
|align="left"|Perugia
|-
|align="left"|{{flagicon|BEL}} [[Moutir Chajia]]
|align="left"|Como
|-
|align="left"|{{flagicon|ITA}} [[Simone Corazza]]
|align="left"|Alessandria
|-
|align="left"|{{flagicon|ITA}} [[Alessandro Deiola]]
|align="left"|Cagliari
|-
|align="left"|{{flagicon|POR}} [[Rafael Leão]]
|align="left"|AC Milan
|-
|align="left"|{{flagicon|URY}} [[César Falletti]]
|rowspan="2" align="left"|Ternana
|-
|align="left"|{{flagicon|ARG}} [[Diego Peralta (pemain sepak bola Argentina)|Diego Peralta]]
|-
|align="left"|{{flagicon|ITA}} [[Gabriele Moncini]]
|align="left"|Benevento
|-
|align="left"|{{flagicon|ARG}} [[Roberto Pereyra]]
|rowspan="2" align="left"|Udinese
|-
|align="left"|{{flagicon|ARG}} [[Ignacio Pussetto]]
|-
|align="left"|{{flagicon|ITA}} [[Fabio Quagliarella]]
|align="left"|Sampdoria
|-
|align="left"|{{flagicon|CHI}} [[Alexis Sánchez]]
|align="left"|Inter Milan
|-
|align="left"|{{flagicon|ITA}} [[Lorenzo Venuti]]
|align="left"|Fiorentina
|}

== Referensi ==
{{Reflist}}

{{Piala Italia}}
{{portal bar|Sepak bola|Italia}}

[[Kategori:Musim Piala Italia|2021–2022]]