Allopregnanolon: Perbedaan antara revisi

Allopregnanolon
Nama
	Nama IUPAC 1-(3-Hidroksi-10,13-dimetil-; 2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradekahidro-; 1H-Siklopenta[a]; fenantren-17-yl)etanon
	Nama lain 3α,5α-Tetrahidroprogesteron
Penanda
Nomor CAS	516-54-1;
Model 3D (JSmol)	Gambar interaktif;
3DMet	{{{3DMet}}}
ChemSpider	17216124;
Nomor EC
PubChem CID	262961;
Nomor RTECS	{{{value}}}
CompTox Dashboard (EPA)	DTXSID901016239 DTXSID1046342, DTXSID901016239 ;
	InChI InChI=1/C21H34O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h14-19,23H,4-12H2,1-3H3/t14?,15-,16+,17-,18+,19+,20+,21-/m1/s1 Key: AURFZBICLPNKBZ-JMTGGFPBBC;
	SMILES CC(=O)[C@H]2CC[C@H]1[C@@H]3CCC4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@@]12C;
Sifat
Rumus kimia	C21H34O2
Massa molar	318,49 g/mol
	Kecuali dinyatakan lain, data di atas berlaku pada suhu dan tekanan standar (25 °C [77 °F], 100 kPa).
	Referensi

Jelajahi riwayat secara interaktif

← Revisi sebelumnya

Konten dihapus Konten ditambahkan

VisualTeks wiki

Sebaris

Revisi terkini sejak 29 Desember 2023 03.14

Allopregnanolon (bahasa Inggris: Allopregnanolone, 3α-hydroxy-5α-pregnan-20-one, 3α,5α-tetrahydroprogesterone, THP, ALLO) merupakan neurosteroid yang mengikat pencerap GABA. ALLO disintesis di dalam otak oleh neuron piramidal^[1] dari progesteron dengan bantuan enzim 5alfa-reduktase tipe I dan 3alfa-hidroksisteroid dehidrogenase.^[2]

Rujukan

^ (Inggris) "Down-regulation of neurosteroid biosynthesis in corticolimbic circuits mediates social isolation-induced behavior in mice". Psychiatric Institute, Department of Psychiatry, School of Medicine, University of Illinois at Chicago; Agís-Balboa RC, Pinna G, Pibiri F, Kadriu B, Costa E, Guidotti A. Diakses tanggal 2010-06-18.
^ (Inggris) "Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesis". Department of Psychiatry, Psychiatric Institute, University of Illinois; Agís-Balboa RC, Pinna G, Zhubi A, Maloku E, Veldic M, Costa E, Guidotti A. Diakses tanggal 2010-06-18.

Artikel bertopik biokimia ini adalah sebuah rintisan. Anda dapat membantu Wikipedia dengan mengembangkannya.

[1] (Inggris) "Down-regulation of neurosteroid biosynthesis in corticolimbic circuits mediates social isolation-induced behavior in mice". Psychiatric Institute, Department of Psychiatry, School of Medicine, University of Illinois at Chicago; Agís-Balboa RC, Pinna G, Pibiri F, Kadriu B, Costa E, Guidotti A. Diakses tanggal 2010-06-18.

[2] (Inggris) "Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesis". Department of Psychiatry, Psychiatric Institute, University of Illinois; Agís-Balboa RC, Pinna G, Zhubi A, Maloku E, Veldic M, Costa E, Guidotti A. Diakses tanggal 2010-06-18.

[1]

[2]

@@ Baris 1: / Baris 1: @@
 {{chembox
-|ImageFile=Allopregnanolone.png
+|ImageFile=Allopregnanolone.svg
 |ImageSize=200px
 |IUPACName=1-(3-Hidroksi-10,13-dimetil-<br />2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradekahidro-<br />1''H''-Siklopenta[a]<br />fenantren-17-yl)etanon
@@ Baris 28: / Baris 28: @@
 }}
-'''Allopregnanolon''' ({{lang-en|Allopregnanolone, 3α-hydroxy-5α-pregnan-20-one, 3α,5α-tetrahydroprogesterone, THP, ALLO}}) merupakan [[neurosteroid]] yang mengikat pencerap GABA. ALLO disintesis di dalam [[otak]] oleh [[neuron]] piramidal<ref>{{en}}{{cite web
+'''Allopregnanolon''' ({{lang-en|Allopregnanolone, 3α-hydroxy-5α-pregnan-20-one, 3α,5α-tetrahydroprogesterone, THP, ALLO}}) merupakan [[neurosteroid]] yang mengikat pencerap GABA. ALLO disintesis di dalam [[otak]] oleh [[neuron]] piramidal<ref>{{en}} {{cite web
 | url          = http://www.ncbi.nlm.nih.gov/pubmed/18003893
 | title        = Down-regulation of neurosteroid biosynthesis in corticolimbic circuits mediates social isolation-induced behavior in mice
 | accessdate   = 2010-06-18
 | work         = Psychiatric Institute, Department of Psychiatry, School of Medicine, University of Illinois at Chicago; Agís-Balboa RC, Pinna G, Pibiri F, Kadriu B, Costa E, Guidotti A.
-}}</ref> dari [[progesteron]] dengan bantuan [[enzim]] 5alfa-reduktase tipe I dan 3alfa-hidroksisteroid [[dehidrogenase]].<ref>{{en}}{{cite web
+}}</ref> dari [[progesteron]] dengan bantuan [[enzim]] 5alfa-reduktase tipe I dan 3alfa-hidroksisteroid [[dehidrogenase]].<ref>{{en}} {{cite web
 | url          = http://www.ncbi.nlm.nih.gov/pubmed/16984997
 | title        = Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesis
@@ Baris 42: / Baris 42: @@
 == Rujukan ==
 {{reflist}}
-{{Biokimia-stub}}
 [[Kategori:Steroid]]
+{{Biokimia-stub}}