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Penisilin G: Perbedaan antara revisi

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'Penisilin G' atau 'Benzilpenisilin' merupakan antibakteri yang digunakan pada pengobatan infeksi tenggorokan, otitis media, endokarditis, penyakit meningokokus, pnemonia, selulitis, antraks, profilaksis amputasi pada lengan atau kaki.<ref>{{Cite web|url=http://pionas.pom.go.id/monografi/benzilpenisilin-penisilin-g|title=BENZILPENISILIN (PENISILIN G) {{!}} PIO Nas|website=pionas.pom.go.id|language=id|access-date=2017-09-21}}</ref>{{Drugbox|Verifiedfields=changed|Watchedfields=changed|verifiedrevid=396298574|IUPAC_name=(2''S'',5''R'',6''R'')-3,3-Dimetil-7-oxo-6-(2-fenilasetamido)-4-thia-1-azabisiklo[3.2.0]heptana-2-asam karboksilat|image=Benzylpenicillin.svg|width=250px|image2=Benzylpenicillin-3D-balls.png|width2=|caption2=Ball and stick model. Legend:<br />Blue=[[nitrogen]]; red=[[oxygen]]; yellow=[[sulphur]]<br />black=[[carbon]] and carbon bonds; white=[[hydrogen]] <!--Clinical data-->|tradename=Pfizerpen, other|synonyms=penisilin G potassium,<ref name=Pro2016>{{cite web|title=Penicillin G Injection - FDA prescribing information, side effects and uses|url=https://www.drugs.com/pro/penicillin-g-injection.html|website=www.drugs.com|accessdate=10 December 2016|deadurl=no|archiveurl=https://web.archive.org/web/20161220230501/https://www.drugs.com/pro/penicillin-g-injection.html|archivedate=20 December 2016|df=dmy-all}}</ref> penicillin G sodium|Drugs.com={{drugs.com|international|Benzylpenicillin}}|MedlinePlus=a685013|pregnancy_AU=A|pregnancy_US=B|legal_status=Rx-only|routes_of_administration=[[Terapi Intravena|IV]], [[Intramuskular|IM]] <!--Pharmacokinetic data-->|protein_bound=60 %|metabolism=[[Hati]]|elimination_half-life=30&nbsp;min|excretion=[[Ginjal]] <!--Identifiers-->|IUPHAR_ligand=4796|CAS_number_Ref={{cascite|correct|??}}|CAS_number=61-33-6|CAS_supplemental=(free acid)<br/>{{CAS|69-57-8}} (sodium salt)|ATC_prefix=J01|ATC_suffix=CE01|ATC_supplemental={{ATC|S01|AA14}} {{ATCvet|J51|CE01}}|PubChem=5904|DrugBank_Ref={{drugbankcite|correct|drugbank}}|DrugBank=DB01053|ChemSpiderID_Ref={{chemspidercite|correct|chemspider}}|ChemSpiderID=5693|UNII_Ref={{fdacite|correct|FDA}}|UNII=Q42T66VG0C|KEGG_Ref={{keggcite|changed|kegg}}|KEGG=D02336|ChEBI_Ref={{ebicite|changed|EBI}}|ChEBI=18208|ChEMBL_Ref={{ebicite|changed|EBI}}|ChEMBL=29 <!--Chemical data-->|C=16|H=18|N=2|O=4|S=1|charge=|molecular_weight=334.4&nbsp;g/mol|SMILES=CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)Cc3ccccc3)C(=O)O)C|StdInChI_Ref={{stdinchicite|correct|chemspider}}|StdInChI=1S/C16H18N2O4S/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22)/t11-,12+,14-/m1/s1|StdInChIKey_Ref={{stdinchicite|correct|chemspider}}|StdInChIKey=JGSARLDLIJGVTE-MBNYWOFBSA-N}}
'''Penisilin G''' atau '''Benzilpenisilin''' merupakan antibakteri yang digunakan pada pengobatan infeksi tenggorokan, otitis media, endokarditis, penyakit meningokokus, pnemonia, selulitis, antraks, profilaksis amputasi pada lengan atau kaki.<ref>{{Cite web|url=http://pionas.pom.go.id/monografi/benzilpenisilin-penisilin-g|title=BENZILPENISILIN (PENISILIN G) {{!}} PIO Nas|website=pionas.pom.go.id|language=id|access-date=2017-09-21}}</ref>{{Drugbox|Verifiedfields=changed|Watchedfields=changed|verifiedrevid=396298574|IUPAC_name=(2''S'',5''R'',6''R'')-3,3-Dimetil-7-oxo-6-(2-fenilasetamido)-4-thia-1-azabisiklo[3.2.0]heptana-2-asam karboksilat|image=Benzylpenicillin.svg|width=250px|image2=Benzylpenicillin-3D-balls.png|width2=|caption2=Ball and stick model. Legend:<br />Blue=[[nitrogen]]; red=[[oxygen]]; yellow=[[sulphur]]<br />black=[[carbon]] and carbon bonds; white=[[hydrogen]] <!--Clinical data-->|tradename=Pfizerpen, other|synonyms=penisilin G potassium,<ref name=Pro2016>{{cite web|title=Penicillin G Injection - FDA prescribing information, side effects and uses|url=https://www.drugs.com/pro/penicillin-g-injection.html|website=www.drugs.com|accessdate=10 December 2016|deadurl=no|archiveurl=https://web.archive.org/web/20161220230501/https://www.drugs.com/pro/penicillin-g-injection.html|archivedate=20 December 2016|df=dmy-all}}</ref> penicillin G sodium|Drugs.com={{drugs.com|international|Benzylpenicillin}}|MedlinePlus=a685013|pregnancy_AU=A|pregnancy_US=B|legal_status=Rx-only|routes_of_administration=[[Terapi Intravena|IV]], [[Intramuskular|IM]] <!--Pharmacokinetic data-->|protein_bound=60 %|metabolism=[[Hati]]|elimination_half-life=30&nbsp;min|excretion=[[Ginjal]] <!--Identifiers-->|IUPHAR_ligand=4796|CAS_number_Ref={{cascite|correct|??}}|CAS_number=61-33-6|CAS_supplemental=(free acid)<br/>{{CAS|69-57-8}} (sodium salt)|ATC_prefix=J01|ATC_suffix=CE01|ATC_supplemental={{ATC|S01|AA14}} {{ATCvet|J51|CE01}}|PubChem=5904|DrugBank_Ref={{drugbankcite|correct|drugbank}}|DrugBank=DB01053|ChemSpiderID_Ref={{chemspidercite|correct|chemspider}}|ChemSpiderID=5693|UNII_Ref={{fdacite|correct|FDA}}|UNII=Q42T66VG0C|KEGG_Ref={{keggcite|changed|kegg}}|KEGG=D02336|ChEBI_Ref={{ebicite|changed|EBI}}|ChEBI=18208|ChEMBL_Ref={{ebicite|changed|EBI}}|ChEMBL=29 <!--Chemical data-->|C=16|H=18|N=2|O=4|S=1|charge=|molecular_weight=334.4&nbsp;g/mol|SMILES=CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)Cc3ccccc3)C(=O)O)C|StdInChI_Ref={{stdinchicite|correct|chemspider}}|StdInChI=1S/C16H18N2O4S/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22)/t11-,12+,14-/m1/s1|StdInChIKey_Ref={{stdinchicite|correct|chemspider}}|StdInChIKey=JGSARLDLIJGVTE-MBNYWOFBSA-N}}
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Revisi per 21 September 2017 13.36

Penisilin G atau Benzilpenisilin merupakan antibakteri yang digunakan pada pengobatan infeksi tenggorokan, otitis media, endokarditis, penyakit meningokokus, pnemonia, selulitis, antraks, profilaksis amputasi pada lengan atau kaki.[1]

Penisilin G
Nama sistematis (IUPAC)
(2S,5R,6R)-3,3-Dimetil-7-oxo-6-(2-fenilasetamido)-4-thia-1-azabisiklo[3.2.0]heptana-2-asam karboksilat
Data klinis
Nama dagang Pfizerpen, other
AHFS/Drugs.com International Drug Names
MedlinePlus a685013
Kat. kehamilan A(AU) B(US)
Status hukum Preskripsi saja
Rute IV, IM
Data farmakokinetik
Ikatan protein 60 %
Metabolisme Hati
Waktu paruh 30 min
Ekskresi Ginjal
Pengenal
Nomor CAS 61-33-6 YaY (free acid)
69-57-8 (sodium salt)
Kode ATC J01CE01 S01AA14 QJ51CE01
PubChem CID 5904
Ligan IUPHAR 4796
DrugBank DB01053
ChemSpider 5693 YaY
UNII Q42T66VG0C YaY
KEGG D02336 N
ChEBI CHEBI:18208 N
ChEMBL CHEMBL29 N
Sinonim penisilin G potassium,[2] penicillin G sodium
Data kimia
Rumus C16H18N2O4S 
Massa mol. 334.4 g/mol
  • InChI=1S/C16H18N2O4S/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22)/t11-,12+,14-/m1/s1 YaY
    Key:JGSARLDLIJGVTE-MBNYWOFBSA-N YaY

  1. ^ "BENZILPENISILIN (PENISILIN G) | PIO Nas". pionas.pom.go.id. Diakses tanggal 2017-09-21. 
  2. ^ "Penicillin G Injection - FDA prescribing information, side effects and uses". www.drugs.com. Diarsipkan dari versi asli tanggal 20 December 2016. Diakses tanggal 10 December 2016.