Penisilin G: Perbedaan antara revisi
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'Penisilin G' atau 'Benzilpenisilin' merupakan antibakteri yang digunakan pada pengobatan infeksi tenggorokan, otitis media, endokarditis, penyakit meningokokus, pnemonia, selulitis, antraks, profilaksis amputasi pada lengan atau kaki.<ref>{{Cite web|url=http://pionas.pom.go.id/monografi/benzilpenisilin-penisilin-g|title=BENZILPENISILIN (PENISILIN G) {{!}} PIO Nas|website=pionas.pom.go.id|language=id|access-date=2017-09-21}}</ref>{{Drugbox|Verifiedfields=changed|Watchedfields=changed|verifiedrevid=396298574|IUPAC_name=(2''S'',5''R'',6''R'')-3,3-Dimetil-7-oxo-6-(2-fenilasetamido)-4-thia-1-azabisiklo[3.2.0]heptana-2-asam karboksilat|image=Benzylpenicillin.svg|width=250px|image2=Benzylpenicillin-3D-balls.png|width2=|caption2=Ball and stick model. Legend:<br />Blue=[[nitrogen]]; red=[[oxygen]]; yellow=[[sulphur]]<br />black=[[carbon]] and carbon bonds; white=[[hydrogen]] <!--Clinical data-->|tradename=Pfizerpen, other|synonyms=penisilin G potassium,<ref name=Pro2016>{{cite web|title=Penicillin G Injection - FDA prescribing information, side effects and uses|url=https://www.drugs.com/pro/penicillin-g-injection.html|website=www.drugs.com|accessdate=10 December 2016|deadurl=no|archiveurl=https://web.archive.org/web/20161220230501/https://www.drugs.com/pro/penicillin-g-injection.html|archivedate=20 December 2016|df=dmy-all}}</ref> penicillin G sodium|Drugs.com={{drugs.com|international|Benzylpenicillin}}|MedlinePlus=a685013|pregnancy_AU=A|pregnancy_US=B|legal_status=Rx-only|routes_of_administration=[[Terapi Intravena|IV]], [[Intramuskular|IM]] <!--Pharmacokinetic data-->|protein_bound=60 %|metabolism=[[Hati]]|elimination_half-life=30 min|excretion=[[Ginjal]] <!--Identifiers-->|IUPHAR_ligand=4796|CAS_number_Ref={{cascite|correct|??}}|CAS_number=61-33-6|CAS_supplemental=(free acid)<br/>{{CAS|69-57-8}} (sodium salt)|ATC_prefix=J01|ATC_suffix=CE01|ATC_supplemental={{ATC|S01|AA14}} {{ATCvet|J51|CE01}}|PubChem=5904|DrugBank_Ref={{drugbankcite|correct|drugbank}}|DrugBank=DB01053|ChemSpiderID_Ref={{chemspidercite|correct|chemspider}}|ChemSpiderID=5693|UNII_Ref={{fdacite|correct|FDA}}|UNII=Q42T66VG0C|KEGG_Ref={{keggcite|changed|kegg}}|KEGG=D02336|ChEBI_Ref={{ebicite|changed|EBI}}|ChEBI=18208|ChEMBL_Ref={{ebicite|changed|EBI}}|ChEMBL=29 <!--Chemical data-->|C=16|H=18|N=2|O=4|S=1|charge=|molecular_weight=334.4 g/mol|SMILES=CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)Cc3ccccc3)C(=O)O)C|StdInChI_Ref={{stdinchicite|correct|chemspider}}|StdInChI=1S/C16H18N2O4S/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22)/t11-,12+,14-/m1/s1|StdInChIKey_Ref={{stdinchicite|correct|chemspider}}|StdInChIKey=JGSARLDLIJGVTE-MBNYWOFBSA-N}} |
'''Penisilin G''' atau '''Benzilpenisilin''' merupakan antibakteri yang digunakan pada pengobatan infeksi tenggorokan, otitis media, endokarditis, penyakit meningokokus, pnemonia, selulitis, antraks, profilaksis amputasi pada lengan atau kaki.<ref>{{Cite web|url=http://pionas.pom.go.id/monografi/benzilpenisilin-penisilin-g|title=BENZILPENISILIN (PENISILIN G) {{!}} PIO Nas|website=pionas.pom.go.id|language=id|access-date=2017-09-21}}</ref>{{Drugbox|Verifiedfields=changed|Watchedfields=changed|verifiedrevid=396298574|IUPAC_name=(2''S'',5''R'',6''R'')-3,3-Dimetil-7-oxo-6-(2-fenilasetamido)-4-thia-1-azabisiklo[3.2.0]heptana-2-asam karboksilat|image=Benzylpenicillin.svg|width=250px|image2=Benzylpenicillin-3D-balls.png|width2=|caption2=Ball and stick model. Legend:<br />Blue=[[nitrogen]]; red=[[oxygen]]; yellow=[[sulphur]]<br />black=[[carbon]] and carbon bonds; white=[[hydrogen]] <!--Clinical data-->|tradename=Pfizerpen, other|synonyms=penisilin G potassium,<ref name=Pro2016>{{cite web|title=Penicillin G Injection - FDA prescribing information, side effects and uses|url=https://www.drugs.com/pro/penicillin-g-injection.html|website=www.drugs.com|accessdate=10 December 2016|deadurl=no|archiveurl=https://web.archive.org/web/20161220230501/https://www.drugs.com/pro/penicillin-g-injection.html|archivedate=20 December 2016|df=dmy-all}}</ref> penicillin G sodium|Drugs.com={{drugs.com|international|Benzylpenicillin}}|MedlinePlus=a685013|pregnancy_AU=A|pregnancy_US=B|legal_status=Rx-only|routes_of_administration=[[Terapi Intravena|IV]], [[Intramuskular|IM]] <!--Pharmacokinetic data-->|protein_bound=60 %|metabolism=[[Hati]]|elimination_half-life=30 min|excretion=[[Ginjal]] <!--Identifiers-->|IUPHAR_ligand=4796|CAS_number_Ref={{cascite|correct|??}}|CAS_number=61-33-6|CAS_supplemental=(free acid)<br/>{{CAS|69-57-8}} (sodium salt)|ATC_prefix=J01|ATC_suffix=CE01|ATC_supplemental={{ATC|S01|AA14}} {{ATCvet|J51|CE01}}|PubChem=5904|DrugBank_Ref={{drugbankcite|correct|drugbank}}|DrugBank=DB01053|ChemSpiderID_Ref={{chemspidercite|correct|chemspider}}|ChemSpiderID=5693|UNII_Ref={{fdacite|correct|FDA}}|UNII=Q42T66VG0C|KEGG_Ref={{keggcite|changed|kegg}}|KEGG=D02336|ChEBI_Ref={{ebicite|changed|EBI}}|ChEBI=18208|ChEMBL_Ref={{ebicite|changed|EBI}}|ChEMBL=29 <!--Chemical data-->|C=16|H=18|N=2|O=4|S=1|charge=|molecular_weight=334.4 g/mol|SMILES=CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)Cc3ccccc3)C(=O)O)C|StdInChI_Ref={{stdinchicite|correct|chemspider}}|StdInChI=1S/C16H18N2O4S/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22)/t11-,12+,14-/m1/s1|StdInChIKey_Ref={{stdinchicite|correct|chemspider}}|StdInChIKey=JGSARLDLIJGVTE-MBNYWOFBSA-N}} |
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Revisi per 21 September 2017 13.36
Penisilin G atau Benzilpenisilin merupakan antibakteri yang digunakan pada pengobatan infeksi tenggorokan, otitis media, endokarditis, penyakit meningokokus, pnemonia, selulitis, antraks, profilaksis amputasi pada lengan atau kaki.[1]
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| Nama sistematis (IUPAC) | |
| (2S,5R,6R)-3,3-Dimetil-7-oxo-6-(2-fenilasetamido)-4-thia-1-azabisiklo[3.2.0]heptana-2-asam karboksilat | |
| Data klinis | |
| Nama dagang | Pfizerpen, other |
| AHFS/Drugs.com | International Drug Names |
| MedlinePlus | a685013 |
| Kat. kehamilan | A(AU) B(US) |
| Status hukum | ℞ Preskripsi saja |
| Rute | IV, IM |
| Data farmakokinetik | |
| Ikatan protein | 60 % |
| Metabolisme | Hati |
| Waktu paruh | 30 min |
| Ekskresi | Ginjal |
| Pengenal | |
| Nomor CAS | 61-33-6  (free acid)69-57-8 (sodium salt) |
| Kode ATC | J01CE01 S01AA14 QJ51CE01 |
| PubChem | CID 5904 |
| Ligan IUPHAR | 4796 |
| DrugBank | DB01053 |
| ChemSpider | 5693
|
| UNII | Q42T66VG0C
|
| KEGG | D02336 
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| ChEBI | CHEBI:18208
|
| ChEMBL | CHEMBL29
|
| Sinonim | penisilin G potassium,[2] penicillin G sodium |
| Data kimia | |
| Rumus | C16H18N2O4S |
| Massa mol. | 334.4 g/mol |
| |
- ^ "BENZILPENISILIN (PENISILIN G) | PIO Nas". pionas.pom.go.id. Diakses tanggal 2017-09-21.
- ^ "Penicillin G Injection - FDA prescribing information, side effects and uses". www.drugs.com. Diarsipkan dari versi asli tanggal 20 December 2016. Diakses tanggal 10 December 2016.