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{{Orphan|date=Desember 2022}}

'''Aulanni'am''' adalah ilmuan [[biokimia]] molekuler di Indonesia. Ia menyelesaikan pendidikan di [[Universitas Airlangga]] dan [[Universidad de Montpellier 2]]. Sejak 2018, ia merupakan Wakil Rektor Bidang Akademik [[Universitas Brawijaya]].<ref>{{Cite news|last=Caesaria|first=Sandra Desi|date=2022-02-12|title=Tak Jadi Tatap Muka, UB Kembali Terapkan Kuliah Daring|url=https://www.kompas.com/edu/read/2022/02/12/204956871/tak-jadi-tatap-muka-ub-kembali-terapkan-kuliah-daring|work=Kompas|access-date=2022-12-20}}</ref> Pada 2022, ia mendapatkan penghargaan Indonesia Healthcare Innovation Award (IHIA) yang diselenggarakan oleh Indonesia Healthcare Forum yang bekerja sama dengan Kementerian Kesehatan, BRIN, BKKBN, dan organisasi-organisasi kesehatan di Indonesia berkat penemuan dan ciptaannya berupa alat deteksi dini penyakit tiroid autoimun berbasis thyroid peroxidase (TPO) dan thyroid stimulating hormone receptor (TSHR).<ref>{{Cite news|last=Aisyah|first=Novia|date=2022-12-05|title=Alat Deteksi Dini Penyakit Tiroid Autoimun Buatan Ilmuwan UB Jadi Jawara|url=https://www.detik.com/edu/edutainment/d-6441352/alat-deteksi-dini-penyakit-tiroid-autoimun-buatan-ilmuwan-ub-jadi-jawara|work=Detik|access-date=2022-12-20}}</ref>
'''Aulanni'am''' adalah ilmuan [[biokimia]] molekuler di Indonesia. Ia menyelesaikan pendidikan di [[Universitas Airlangga]] dan [[Universidad de Montpellier 2]]. Sejak 2018, ia merupakan Wakil Rektor Bidang Akademik [[Universitas Brawijaya]].<ref>{{Cite news|last=Caesaria|first=Sandra Desi|date=2022-02-12|title=Tak Jadi Tatap Muka, UB Kembali Terapkan Kuliah Daring|url=https://www.kompas.com/edu/read/2022/02/12/204956871/tak-jadi-tatap-muka-ub-kembali-terapkan-kuliah-daring|work=Kompas|access-date=2022-12-20}}</ref> Pada 2022, ia mendapatkan penghargaan Indonesia Healthcare Innovation Award (IHIA) yang diselenggarakan oleh Indonesia Healthcare Forum yang bekerja sama dengan Kementerian Kesehatan, BRIN, BKKBN, dan organisasi-organisasi kesehatan di Indonesia berkat penemuan dan ciptaannya berupa alat deteksi dini penyakit tiroid autoimun berbasis thyroid peroxidase (TPO) dan thyroid stimulating hormone receptor (TSHR).<ref>{{Cite news|last=Aisyah|first=Novia|date=2022-12-05|title=Alat Deteksi Dini Penyakit Tiroid Autoimun Buatan Ilmuwan UB Jadi Jawara|url=https://www.detik.com/edu/edutainment/d-6441352/alat-deteksi-dini-penyakit-tiroid-autoimun-buatan-ilmuwan-ub-jadi-jawara|work=Detik|access-date=2022-12-20}}</ref>


Baris 6: Baris 8:


# Akmal, Muslim; Aulanni'am, Aulanni'am; Widodo, M. Aris; Sumitro, Sutiman B.; Purnomo, Basuki B.; Widodo (2016-09-01). "The important role of protamine in spermatogenesis and quality of sperm: A mini review". ''Asian Pacific Journal of Reproduction'' (dalam bahasa Inggris). '''5''' (5): 357–360. [[Digital object identifier|doi]]:10.1016/j.apjr.2016.07.013. [[International Standard Serial Number|ISSN]]&nbsp;2305-0500.
# Akmal, Muslim; Aulanni'am, Aulanni'am; Widodo, M. Aris; Sumitro, Sutiman B.; Purnomo, Basuki B.; Widodo (2016-09-01). "The important role of protamine in spermatogenesis and quality of sperm: A mini review". ''Asian Pacific Journal of Reproduction'' (dalam bahasa Inggris). '''5''' (5): 357–360. [[Digital object identifier|doi]]:10.1016/j.apjr.2016.07.013. [[International Standard Serial Number|ISSN]]&nbsp;2305-0500.
# Haryadi, Linda; Suprayitno, Eddy; Aulanni'am, Aulanni'am; Hariati, Anik Martinah (2019-10). "Immune response evaluation in Balb/c mice after crude extract of Anisakis typica sensitization". ''October-2019'' (dalam bahasa Inggris). '''12''' (10): 1529–1534. [[Digital object identifier|doi]]:10.14202/vetworld.2019.1529-1534. [[International Standard Serial Number|ISSN]]&nbsp;2231-0916. [[PubMed Central|PMC]]&nbsp;6868255&#x202F;[[Berkas:Lock-green.svg|pra=|al=alt=Dapat diakses gratis|14x14px|Dapat diakses gratis]]. [[PubMed Identifier|PMID]]&nbsp;31849412.
# Haryadi, Linda; Suprayitno, Eddy; Aulanni'am, Aulanni'am; Hariati, Anik Martinah (2019-10). "Immune response evaluation in Balb/c mice after crude extract of Anisakis typica sensitization". ''October-2019'' (dalam bahasa Inggris). '''12''' (10): 1529–1534. [[Digital object identifier|doi]]:10.14202/vetworld.2019.1529-1534. [[International Standard Serial Number|ISSN]]&nbsp;2231-0916. [[PubMed Central|PMC]]&nbsp;6868255 [[Berkas:Lock-green.svg|pra=|al=alt=Dapat diakses gratis|14x14px|Dapat diakses gratis]]. [[PubMed Identifier|PMID]]&nbsp;31849412.
# Sakti, Setyawan P.; Chabibah, Nur; Ayu, Senja P.; Padaga, Masdiana C.; Aulanni’am, Aulanni’am (2015-12-28). "Development of QCM Biosensor with Specific Cow Milk Protein Antibody for Candidate Milk Adulteration Detection". ''Journal of Sensors''. '''2016''': e1807647. [[Digital object identifier|doi]]:10.1155/2016/1807647. [[International Standard Serial Number|ISSN]]&nbsp;1687-725X.
# Sakti, Setyawan P.; Chabibah, Nur; Ayu, Senja P.; Padaga, Masdiana C.; Aulanni’am, Aulanni’am (2015-12-28). "Development of QCM Biosensor with Specific Cow Milk Protein Antibody for Candidate Milk Adulteration Detection". ''Journal of Sensors''. '''2016''': e1807647. [[Digital object identifier|doi]]:10.1155/2016/1807647. [[International Standard Serial Number|ISSN]]&nbsp;1687-725X.
# Kurniawati, Siti; Soedarsono, Soedarsono; Aulanni’am, Aulanni’am; Mertaniasih, Ni Made (2018-06-18). "SINGLE NUCLEOTIDE POLYMORPHISM OF ECCB5 GENE OF MYCOBACTERIUM TUBERCULOSIS COMPLEX ISOLATES FROM SUSPECTED PULMONARY TB PATIENTS IN SURABAYA INDONESIA". ''African Journal of Infectious Diseases (AJID)'' (dalam bahasa Inggris). '''12''' (2): 37–42. [[Digital object identifier|doi]]:10.21010/Ajid.v12i2.6. [[International Standard Serial Number|ISSN]]&nbsp;2505-0419. [[PubMed Central|PMC]]&nbsp;6085738&#x202F;[[Berkas:Lock-green.svg|pra=|al=alt=Dapat diakses gratis|14x14px|Dapat diakses gratis]]. [[PubMed Identifier|PMID]]&nbsp;30109284.
# Kurniawati, Siti; Soedarsono, Soedarsono; Aulanni’am, Aulanni’am; Mertaniasih, Ni Made (2018-06-18). "SINGLE NUCLEOTIDE POLYMORPHISM OF ECCB5 GENE OF MYCOBACTERIUM TUBERCULOSIS COMPLEX ISOLATES FROM SUSPECTED PULMONARY TB PATIENTS IN SURABAYA INDONESIA". ''African Journal of Infectious Diseases (AJID)'' (dalam bahasa Inggris). '''12''' (2): 37–42. [[Digital object identifier|doi]]:10.21010/Ajid.v12i2.6. [[International Standard Serial Number|ISSN]]&nbsp;2505-0419. [[PubMed Central|PMC]]&nbsp;6085738 [[Berkas:Lock-green.svg|pra=|al=alt=Dapat diakses gratis|14x14px|Dapat diakses gratis]]. [[PubMed Identifier|PMID]]&nbsp;30109284.
# Kiptiyah, Kiptiyah; Widodo, Widodo; Ciptadi, Gatot; Aulanni'am, Aulanni'am; Widodo, Mohammad A.; Sumitro, Sutiman B. (2017-10-01). "10-Gingerol as an inducer of apoptosis through HTR1A in cumulus cells: In-vitro and in-silico studies". ''Journal of Taibah University Medical Sciences'' (dalam bahasa Inggris). '''12''' (5): 397–406. [[Digital object identifier|doi]]:10.1016/j.jtumed.2017.05.012. [[International Standard Serial Number|ISSN]]&nbsp;1658-3612. [[PubMed Central|PMC]]&nbsp;6695051&#x202F;[[Berkas:Lock-green.svg|pra=|al=alt=Dapat diakses gratis|14x14px|Dapat diakses gratis]]. [[PubMed Identifier|PMID]]&nbsp;31435270.
# Kiptiyah, Kiptiyah; Widodo, Widodo; Ciptadi, Gatot; Aulanni'am, Aulanni'am; Widodo, Mohammad A.; Sumitro, Sutiman B. (2017-10-01). "10-Gingerol as an inducer of apoptosis through HTR1A in cumulus cells: In-vitro and in-silico studies". ''Journal of Taibah University Medical Sciences'' (dalam bahasa Inggris). '''12''' (5): 397–406. [[Digital object identifier|doi]]:10.1016/j.jtumed.2017.05.012. [[International Standard Serial Number|ISSN]]&nbsp;1658-3612. [[PubMed Central|PMC]]&nbsp;6695051 [[Berkas:Lock-green.svg|pra=|al=alt=Dapat diakses gratis|14x14px|Dapat diakses gratis]]. [[PubMed Identifier|PMID]]&nbsp;31435270.
# Ulhaq, Zulvikar Syambani; Kristanti, Risma Aprinda; Hidayatullah, Achmad Arief; Rachma, Lailia Nur; Susanti, Nurlaili; Aulanni'am, Aulanni'am (2020-10-01). "Data on attitudes, religious perspectives, and practices towards COVID-19 among Indonesian residents: a quick online cross-sectional survey". ''Data in Brief'' (dalam bahasa Inggris). '''32''': 106277. [[Digital object identifier|doi]]:10.1016/j.dib.2020.106277. [[International Standard Serial Number|ISSN]]&nbsp;2352-3409. [[PubMed Central|PMC]]&nbsp;7494484&#x202F;[[Berkas:Lock-green.svg|pra=|al=alt=Dapat diakses gratis|14x14px|Dapat diakses gratis]]. [[PubMed Identifier|PMID]]&nbsp;32984470.
# Ulhaq, Zulvikar Syambani; Kristanti, Risma Aprinda; Hidayatullah, Achmad Arief; Rachma, Lailia Nur; Susanti, Nurlaili; Aulanni'am, Aulanni'am (2020-10-01). "Data on attitudes, religious perspectives, and practices towards COVID-19 among Indonesian residents: a quick online cross-sectional survey". ''Data in Brief'' (dalam bahasa Inggris). '''32''': 106277. [[Digital object identifier|doi]]:10.1016/j.dib.2020.106277. [[International Standard Serial Number|ISSN]]&nbsp;2352-3409. [[PubMed Central|PMC]]&nbsp;7494484 [[Berkas:Lock-green.svg|pra=|al=alt=Dapat diakses gratis|14x14px|Dapat diakses gratis]]. [[PubMed Identifier|PMID]]&nbsp;32984470.
# Kurniawati, Siti; Mertaniasih, Ni Made; Ato, Manabu; Tamura, Toshiki; Soedarsono, Soedarsono; Aulanni'am, Aulanni'am; Mori, Shigetarou; Maeda, Yumi; Mukai, Tetsu (2020-12-01). "Cloning and Protein Expression of eccB5 Gene in ESX-5 System from Mycobacterium tuberculosis". ''BioResearch Open Access''. '''9''' (1): 86–93. [[Digital object identifier|doi]]:10.1089/biores.2019.0019. [[PubMed Central|PMC]]&nbsp;7133456&#x202F;[[Berkas:Lock-green.svg|pra=|al=alt=Dapat diakses gratis|14x14px|Dapat diakses gratis]]. [[PubMed Identifier|PMID]]&nbsp;32257624.
# Kurniawati, Siti; Mertaniasih, Ni Made; Ato, Manabu; Tamura, Toshiki; Soedarsono, Soedarsono; Aulanni'am, Aulanni'am; Mori, Shigetarou; Maeda, Yumi; Mukai, Tetsu (2020-12-01). "Cloning and Protein Expression of eccB5 Gene in ESX-5 System from Mycobacterium tuberculosis". ''BioResearch Open Access''. '''9''' (1): 86–93. [[Digital object identifier|doi]]:10.1089/biores.2019.0019. [[PubMed Central|PMC]]&nbsp;7133456 [[Berkas:Lock-green.svg|pra=|al=alt=Dapat diakses gratis|14x14px|Dapat diakses gratis]]. [[PubMed Identifier|PMID]]&nbsp;32257624.
# Sribudiani, Yunia; Marwan, Deinike W.; Aulanni’am, Aulanni’am; Widodo, Muhammad A.; Purnomo, Basuki B.; Panigoro, Ramdan; Utomo, Ahmad (2018-08-01). "Germline Mutations and Polymorphisms of Androgen Receptor in Prostate Cancer Patients: Frequency and Results of in Silico Analysis". ''Asian Pacific Journal of Cancer Prevention''. '''19''' (8): 2241–2245. [[Digital object identifier|doi]]:10.22034/APJCP.2018.19.8.2241. [[International Standard Serial Number|ISSN]]&nbsp;1513-7368. [[PubMed Central|PMC]]&nbsp;6171394&#x202F;[[Berkas:Lock-green.svg|pra=|al=alt=Dapat diakses gratis|14x14px|Dapat diakses gratis]]. [[PubMed Identifier|PMID]]&nbsp;30139231.
# Sribudiani, Yunia; Marwan, Deinike W.; Aulanni’am, Aulanni’am; Widodo, Muhammad A.; Purnomo, Basuki B.; Panigoro, Ramdan; Utomo, Ahmad (2018-08-01). "Germline Mutations and Polymorphisms of Androgen Receptor in Prostate Cancer Patients: Frequency and Results of in Silico Analysis". ''Asian Pacific Journal of Cancer Prevention''. '''19''' (8): 2241–2245. [[Digital object identifier|doi]]:10.22034/APJCP.2018.19.8.2241. [[International Standard Serial Number|ISSN]]&nbsp;1513-7368. [[PubMed Central|PMC]]&nbsp;6171394 [[Berkas:Lock-green.svg|pra=|al=alt=Dapat diakses gratis|14x14px|Dapat diakses gratis]]. [[PubMed Identifier|PMID]]&nbsp;30139231.
# Kiptiyah, Kiptiyah; Widodo, Widodo; Ciptadi, Gatot; Aulanni’Am, Aulanni’am; Widodo, Mohammad A.; Sumitro, Sutiman B. (2020-12-01). "10-gingerol induces oxidative stress through HTR1A in cumulus cells: in-vitro and in-silico studies". ''Journal of Complementary and Integrative Medicine'' (dalam bahasa Inggris). '''17''' (4). [[Digital object identifier|doi]]:10.1515/jcim-2019-0042. [[International Standard Serial Number|ISSN]]&nbsp;1553-3840.
# Kiptiyah, Kiptiyah; Widodo, Widodo; Ciptadi, Gatot; Aulanni’Am, Aulanni’am; Widodo, Mohammad A.; Sumitro, Sutiman B. (2020-12-01). "10-gingerol induces oxidative stress through HTR1A in cumulus cells: in-vitro and in-silico studies". ''Journal of Complementary and Integrative Medicine'' (dalam bahasa Inggris). '''17''' (4). [[Digital object identifier|doi]]:10.1515/jcim-2019-0042. [[International Standard Serial Number|ISSN]]&nbsp;1553-3840.
# Dewi, Nadia Artha; Aulanni’am, Aulanni'am; Sujuti, Hidayat; Widodo, Muhammad Aris; Soeatmadji, Djoko Wahono (20180313). "Mechanism of retinal pericyte migration through Angiopoietin/Tie-2 signaling pathway on diabetic rats". ''International Journal of Ophthalmology'' (dalam bahasa Inggris). '''11''' (3): 375–381. [[Digital object identifier|doi]]:10.18240/ijo.2018.03.05. [[PubMed Central|PMC]]&nbsp;5861225&#x202F;[[Berkas:Lock-green.svg|pra=|al=alt=Dapat diakses gratis|14x14px|Dapat diakses gratis]]. [[PubMed Identifier|PMID]]&nbsp;29600169.
# Dewi, Nadia Artha; Aulanni’am, Aulanni'am; Sujuti, Hidayat; Widodo, Muhammad Aris; Soeatmadji, Djoko Wahono (20180313). "Mechanism of retinal pericyte migration through Angiopoietin/Tie-2 signaling pathway on diabetic rats". ''International Journal of Ophthalmology'' (dalam bahasa Inggris). '''11''' (3): 375–381. [[Digital object identifier|doi]]:10.18240/ijo.2018.03.05. [[PubMed Central|PMC]]&nbsp;5861225 [[Berkas:Lock-green.svg|pra=|al=alt=Dapat diakses gratis|14x14px|Dapat diakses gratis]]. [[PubMed Identifier|PMID]]&nbsp;29600169.


== Referensi ==
== Referensi ==
<references />
<references />

[[Kategori:Ilmuwan Indonesia]]
[[Kategori:Ilmuwan Indonesia]]
[[Kategori:Kimia]]
[[Kategori:Kimia]]

Revisi terkini sejak 26 Desember 2022 12.57


Aulanni'am adalah ilmuan biokimia molekuler di Indonesia. Ia menyelesaikan pendidikan di Universitas Airlangga dan Universidad de Montpellier 2. Sejak 2018, ia merupakan Wakil Rektor Bidang Akademik Universitas Brawijaya.[1] Pada 2022, ia mendapatkan penghargaan Indonesia Healthcare Innovation Award (IHIA) yang diselenggarakan oleh Indonesia Healthcare Forum yang bekerja sama dengan Kementerian Kesehatan, BRIN, BKKBN, dan organisasi-organisasi kesehatan di Indonesia berkat penemuan dan ciptaannya berupa alat deteksi dini penyakit tiroid autoimun berbasis thyroid peroxidase (TPO) dan thyroid stimulating hormone receptor (TSHR).[2]

  1. Akmal, Muslim; Aulanni'am, Aulanni'am; Widodo, M. Aris; Sumitro, Sutiman B.; Purnomo, Basuki B.; Widodo (2016-09-01). "The important role of protamine in spermatogenesis and quality of sperm: A mini review". Asian Pacific Journal of Reproduction (dalam bahasa Inggris). 5 (5): 357–360. doi:10.1016/j.apjr.2016.07.013. ISSN 2305-0500.
  2. Haryadi, Linda; Suprayitno, Eddy; Aulanni'am, Aulanni'am; Hariati, Anik Martinah (2019-10). "Immune response evaluation in Balb/c mice after crude extract of Anisakis typica sensitization". October-2019 (dalam bahasa Inggris). 12 (10): 1529–1534. doi:10.14202/vetworld.2019.1529-1534. ISSN 2231-0916. PMC 6868255 alt=Dapat diakses gratis. PMID 31849412.
  3. Sakti, Setyawan P.; Chabibah, Nur; Ayu, Senja P.; Padaga, Masdiana C.; Aulanni’am, Aulanni’am (2015-12-28). "Development of QCM Biosensor with Specific Cow Milk Protein Antibody for Candidate Milk Adulteration Detection". Journal of Sensors. 2016: e1807647. doi:10.1155/2016/1807647. ISSN 1687-725X.
  4. Kurniawati, Siti; Soedarsono, Soedarsono; Aulanni’am, Aulanni’am; Mertaniasih, Ni Made (2018-06-18). "SINGLE NUCLEOTIDE POLYMORPHISM OF ECCB5 GENE OF MYCOBACTERIUM TUBERCULOSIS COMPLEX ISOLATES FROM SUSPECTED PULMONARY TB PATIENTS IN SURABAYA INDONESIA". African Journal of Infectious Diseases (AJID) (dalam bahasa Inggris). 12 (2): 37–42. doi:10.21010/Ajid.v12i2.6. ISSN 2505-0419. PMC 6085738 alt=Dapat diakses gratis. PMID 30109284.
  5. Kiptiyah, Kiptiyah; Widodo, Widodo; Ciptadi, Gatot; Aulanni'am, Aulanni'am; Widodo, Mohammad A.; Sumitro, Sutiman B. (2017-10-01). "10-Gingerol as an inducer of apoptosis through HTR1A in cumulus cells: In-vitro and in-silico studies". Journal of Taibah University Medical Sciences (dalam bahasa Inggris). 12 (5): 397–406. doi:10.1016/j.jtumed.2017.05.012. ISSN 1658-3612. PMC 6695051 alt=Dapat diakses gratis. PMID 31435270.
  6. Ulhaq, Zulvikar Syambani; Kristanti, Risma Aprinda; Hidayatullah, Achmad Arief; Rachma, Lailia Nur; Susanti, Nurlaili; Aulanni'am, Aulanni'am (2020-10-01). "Data on attitudes, religious perspectives, and practices towards COVID-19 among Indonesian residents: a quick online cross-sectional survey". Data in Brief (dalam bahasa Inggris). 32: 106277. doi:10.1016/j.dib.2020.106277. ISSN 2352-3409. PMC 7494484 alt=Dapat diakses gratis. PMID 32984470.
  7. Kurniawati, Siti; Mertaniasih, Ni Made; Ato, Manabu; Tamura, Toshiki; Soedarsono, Soedarsono; Aulanni'am, Aulanni'am; Mori, Shigetarou; Maeda, Yumi; Mukai, Tetsu (2020-12-01). "Cloning and Protein Expression of eccB5 Gene in ESX-5 System from Mycobacterium tuberculosis". BioResearch Open Access. 9 (1): 86–93. doi:10.1089/biores.2019.0019. PMC 7133456 alt=Dapat diakses gratis. PMID 32257624.
  8. Sribudiani, Yunia; Marwan, Deinike W.; Aulanni’am, Aulanni’am; Widodo, Muhammad A.; Purnomo, Basuki B.; Panigoro, Ramdan; Utomo, Ahmad (2018-08-01). "Germline Mutations and Polymorphisms of Androgen Receptor in Prostate Cancer Patients: Frequency and Results of in Silico Analysis". Asian Pacific Journal of Cancer Prevention. 19 (8): 2241–2245. doi:10.22034/APJCP.2018.19.8.2241. ISSN 1513-7368. PMC 6171394 alt=Dapat diakses gratis. PMID 30139231.
  9. Kiptiyah, Kiptiyah; Widodo, Widodo; Ciptadi, Gatot; Aulanni’Am, Aulanni’am; Widodo, Mohammad A.; Sumitro, Sutiman B. (2020-12-01). "10-gingerol induces oxidative stress through HTR1A in cumulus cells: in-vitro and in-silico studies". Journal of Complementary and Integrative Medicine (dalam bahasa Inggris). 17 (4). doi:10.1515/jcim-2019-0042. ISSN 1553-3840.
  10. Dewi, Nadia Artha; Aulanni’am, Aulanni'am; Sujuti, Hidayat; Widodo, Muhammad Aris; Soeatmadji, Djoko Wahono (20180313). "Mechanism of retinal pericyte migration through Angiopoietin/Tie-2 signaling pathway on diabetic rats". International Journal of Ophthalmology (dalam bahasa Inggris). 11 (3): 375–381. doi:10.18240/ijo.2018.03.05. PMC 5861225 alt=Dapat diakses gratis. PMID 29600169.

Referensi

[sunting | sunting sumber]
  1. ^ Caesaria, Sandra Desi (2022-02-12). "Tak Jadi Tatap Muka, UB Kembali Terapkan Kuliah Daring". Kompas. Diakses tanggal 2022-12-20. 
  2. ^ Aisyah, Novia (2022-12-05). "Alat Deteksi Dini Penyakit Tiroid Autoimun Buatan Ilmuwan UB Jadi Jawara". Detik. Diakses tanggal 2022-12-20.