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Revisi terkini sejak 8 Juli 2021 07.57

Dalam bidang studi genetika, AP-1 (bahasa Inggris: activator protein 1, AP-1) adalah protein di dalam inti sel berbentuk heterodimerik dari kompleks fos, jun^[1] dan subgroup ATF,^[2] yang merupakan faktor transkripsi yang memiliki peran penting dalam ekspresi genetik seluler seperti transformasi, proliferasi melalui represi ekspresi gen supresor tumor, diferensiasi, apoptosis, migrasi sel;^[3] mengendalikan ekspresi dan fungsi regulator siklus sel seperti siklin D1, supresor tumor p53, p21(cip1/waf1), p19(ARF) dan p16; dan peradangan.

Rujukan

^ (Inggris) "A role for AP-1 in apoptosis: the case for and against". Department of Developmental Biology, Fernbach Building, Institut Pasteur; Ameyar M, Wisniewska M, Weitzman JB. Diakses tanggal 2010-09-18.
^ (Inggris) "AP-1 in cell proliferation and survival". Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, University of California San Diego; Shaulian E, Karin M. Diakses tanggal 2010-09-18.
^ (Inggris) "AP-1--The Jun proteins: Oncogenes or tumor suppressors in disguise?". Department of Biochemistry and Molecular Biology, The Institute for Medical Research-Israel-Canada, The Hebrew University-Hadassah Medical School; Shaulian E. Diakses tanggal 2010-09-18.

Artikel bertopik genetika ini adalah sebuah rintisan. Anda dapat membantu Wikipedia dengan mengembangkannya.

[1] (Inggris) "A role for AP-1 in apoptosis: the case for and against". Department of Developmental Biology, Fernbach Building, Institut Pasteur; Ameyar M, Wisniewska M, Weitzman JB. Diakses tanggal 2010-09-18.

[2] (Inggris) "AP-1 in cell proliferation and survival". Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, University of California San Diego; Shaulian E, Karin M. Diakses tanggal 2010-09-18.

[3] (Inggris) "AP-1--The Jun proteins: Oncogenes or tumor suppressors in disguise?". Department of Biochemistry and Molecular Biology, The Institute for Medical Research-Israel-Canada, The Hebrew University-Hadassah Medical School; Shaulian E. Diakses tanggal 2010-09-18.

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-Dalam bidang studi [[genetika]], '''AP-1''' ({{lang-en|activator protein 1, AP-1}}) adalah [[protein]] di dalam [[inti sel]] berbentuk heterodimerik dari kompleks [[fos]], [[jun]]<ref>{{en}} {{cite web|url=http://www.ncbi.nlm.nih.gov/pubmed/14585541|title=A role for AP-1 in apoptosis: the case for and against|accessdate=2010-09-18|work=Department of Developmental Biology, Fernbach Building, Institut Pasteur; Ameyar M, Wisniewska M, Weitzman JB.}}</ref> dan subgroup [[ATF]],<ref>{{en}} {{cite web|url=http://www.ncbi.nlm.nih.gov//pubmed/11402335|title=AP-1 in cell proliferation and survival|accessdate=2010-09-18|work=Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, University of California San Diego; Shaulian E, Karin M.}}</ref> yang merupakan [[faktor transkripsi]] yang memiliki peran penting dalam ekspresi genetik selular seperti [[transformasi]], [[proliferasi]] melalui represi ekspresi gen supresor [[tumor]], [[diferensiasi]], [[apoptosis]], migrasi<ref>{{en}} {{cite web|url=http://www.ncbi.nlm.nih.gov/pubmed/20060892|title=AP-1--The Jun proteins: Oncogenes or tumor suppressors in disguise?|accessdate=2010-09-18|work=Department of Biochemistry and Molecular Biology, The Institute for Medical Research-Israel-Canada, The Hebrew University-Hadassah Medical School; Shaulian E.}}</ref> [[sel (biologi)|sel]]; mengendalikan ekspresi dan fungsi regulator [[siklus sel]] seperti siklin D1, supresor tumor p53, p21(cip1/waf1), p19(ARF) dan p16; dan [[peradangan]].
+Dalam bidang studi [[genetika]], '''AP-1''' ({{lang-en|activator protein 1, AP-1}}) adalah [[protein]] di dalam [[inti sel]] berbentuk heterodimerik dari kompleks [[fos]], [[jun]]<ref>{{en}} {{cite web|url=http://www.ncbi.nlm.nih.gov/pubmed/14585541|title=A role for AP-1 in apoptosis: the case for and against|accessdate=2010-09-18|work=Department of Developmental Biology, Fernbach Building, Institut Pasteur; Ameyar M, Wisniewska M, Weitzman JB.}}</ref> dan subgroup [[ATF]],<ref>{{en}} {{cite web|url=http://www.ncbi.nlm.nih.gov//pubmed/11402335|title=AP-1 in cell proliferation and survival|accessdate=2010-09-18|work=Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, University of California San Diego; Shaulian E, Karin M.}}</ref> yang merupakan [[faktor transkripsi]] yang memiliki peran penting dalam ekspresi genetik seluler seperti [[transformasi]], [[proliferasi]] melalui represi ekspresi gen supresor [[tumor]], [[diferensiasi]], [[apoptosis]], migrasi [[sel (biologi)|sel]];<ref>{{en}} {{cite web|url=http://www.ncbi.nlm.nih.gov/pubmed/20060892|title=AP-1--The Jun proteins: Oncogenes or tumor suppressors in disguise?|accessdate=2010-09-18|work=Department of Biochemistry and Molecular Biology, The Institute for Medical Research-Israel-Canada, The Hebrew University-Hadassah Medical School; Shaulian E.}}</ref> mengendalikan ekspresi dan fungsi regulator [[siklus sel]] seperti siklin D1, supresor tumor p53, p21(cip1/waf1), p19(ARF) dan p16; dan [[peradangan]].
 == Rujukan ==
 {{reflist}}
 {{Hormon}}
-{{Genetika-stub}}
+{{Authority control}}
 [[Kategori:Faktor transkripsi]]
-[[en:AP-1 transcription factor]]
+{{Genetika-stub}}
-[[es:Factor de transcripción AP-1]]
-[[ja:AP-1]]
-[[pl:AP-1]]