Protein FLICE-i: Perbedaan antara revisi
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'''Protein FLICE-i''' ({{lang-en|FLICE-inhibitory protein, CASP8 and FADD-like apoptosis regulator, FADD-like IL-1beta-converting enzyme inhibitory protein, FLIP}}) adalah [[faktor transkripsi]] dengan berkas [[gen |
'''Protein FLICE-i''' ({{lang-en|FLICE-inhibitory protein, CASP8 and FADD-like apoptosis regulator, FADD-like IL-1beta-converting enzyme inhibitory protein, FLIP}}) adalah [[faktor transkripsi]] dengan berkas [[gen]]etik CFLAR pada [[kromosom 2 (manusia)|kromosom 2]] lokasi 2q33-q34,<ref>{{en}} {{cite web |
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| url = http://www.ncbi.nlm.nih.gov/gene/8837 |
| url = http://www.ncbi.nlm.nih.gov/gene/8837 |
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| title = CFLAR CASP8 and FADD-like apoptosis regulator [ Homo sapiens ] |
| title = CFLAR CASP8 and FADD-like apoptosis regulator [ Homo sapiens ] |
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| accessdate = 2010-10-26 |
| accessdate = 2010-10-26 |
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| work = Entrez Gene |
| work = Entrez Gene |
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}}</ref> yang banyak terdapat pada [[jaringan otot]] dan [[jaringan limfoid]],<ref>{{en}}{{cite web |
}}</ref> yang banyak terdapat pada [[jaringan otot]] dan [[jaringan limfoid]],<ref>{{en}} {{cite web |
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| url = http://www.ncbi.nlm.nih.gov/pubmed/9217161 |
| url = http://www.ncbi.nlm.nih.gov/pubmed/9217161 |
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| title = Inhibition of death receptor signals by cellular FLIP |
| title = Inhibition of death receptor signals by cellular FLIP |
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}}</ref> sebagai regulator [[apoptosis]]. |
}}</ref> sebagai regulator [[apoptosis]]. |
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Overekspresi FLIP dapat melindungi [[sel tumor]] dari mekanisme [[apoptosis]].<ref>{{en}}{{cite web |
Overekspresi FLIP dapat melindungi [[sel tumor]] dari mekanisme [[apoptosis]].<ref>{{en}} {{cite web |
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| url = http://www.ncbi.nlm.nih.gov/pubmed/16441226 |
| url = http://www.ncbi.nlm.nih.gov/pubmed/16441226 |
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| title = The role of cellular FLICE inhibitory protein (c-FLIP) in the pathogenesis and treatment of cancer |
| title = The role of cellular FLICE inhibitory protein (c-FLIP) in the pathogenesis and treatment of cancer |
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[[Kategori:Faktor transkripsi]] |
[[Kategori:Faktor transkripsi]] |
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[[en:CFLAR]] |
Revisi terkini sejak 29 November 2019 13.07
Protein FLICE-i (bahasa Inggris: FLICE-inhibitory protein, CASP8 and FADD-like apoptosis regulator, FADD-like IL-1beta-converting enzyme inhibitory protein, FLIP) adalah faktor transkripsi dengan berkas genetik CFLAR pada kromosom 2 lokasi 2q33-q34,[1] yang banyak terdapat pada jaringan otot dan jaringan limfoid,[2] sebagai regulator apoptosis.
Overekspresi FLIP dapat melindungi sel tumor dari mekanisme apoptosis.[3]
Rujukan
[sunting | sunting sumber]- ^ (Inggris) "CFLAR CASP8 and FADD-like apoptosis regulator [ Homo sapiens ]". Entrez Gene. Diakses tanggal 2010-10-26.
- ^ (Inggris) "Inhibition of death receptor signals by cellular FLIP". Institute of Biochemistry, Lausanne branch, University of Lausanne; Irmler M, Thome M, Hahne M, Schneider P, Hofmann K, Steiner V, Bodmer JL, Schröter M, Burns K, Mattmann C, Rimoldi D, French LE, Tschopp J. Diakses tanggal 2010-10-26.
- ^ (Inggris) "The role of cellular FLICE inhibitory protein (c-FLIP) in the pathogenesis and treatment of cancer". Cancer Research UK Institute for Cancer Studies, Division of Cancer Studies, Department of Pathology, The Medical School, University of Birmingham; Dutton A, Young LS, Murray PG. Diakses tanggal 2010-10-26.