Protein FLICE-i: Perbedaan antara revisi

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Revisi terkini sejak 29 November 2019 13.07

Protein FLICE-i (bahasa Inggris: FLICE-inhibitory protein, CASP8 and FADD-like apoptosis regulator, FADD-like IL-1beta-converting enzyme inhibitory protein, FLIP) adalah faktor transkripsi dengan berkas genetik CFLAR pada kromosom 2 lokasi 2q33-q34,^[1] yang banyak terdapat pada jaringan otot dan jaringan limfoid,^[2] sebagai regulator apoptosis.

Overekspresi FLIP dapat melindungi sel tumor dari mekanisme apoptosis.^[3]

Rujukan

^ (Inggris) "CFLAR CASP8 and FADD-like apoptosis regulator [ Homo sapiens ]". Entrez Gene. Diakses tanggal 2010-10-26.
^ (Inggris) "Inhibition of death receptor signals by cellular FLIP". Institute of Biochemistry, Lausanne branch, University of Lausanne; Irmler M, Thome M, Hahne M, Schneider P, Hofmann K, Steiner V, Bodmer JL, Schröter M, Burns K, Mattmann C, Rimoldi D, French LE, Tschopp J. Diakses tanggal 2010-10-26.
^ (Inggris) "The role of cellular FLICE inhibitory protein (c-FLIP) in the pathogenesis and treatment of cancer". Cancer Research UK Institute for Cancer Studies, Division of Cancer Studies, Department of Pathology, The Medical School, University of Birmingham; Dutton A, Young LS, Murray PG. Diakses tanggal 2010-10-26.

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[1] (Inggris) "CFLAR CASP8 and FADD-like apoptosis regulator [ Homo sapiens ]". Entrez Gene. Diakses tanggal 2010-10-26.

[2] (Inggris) "Inhibition of death receptor signals by cellular FLIP". Institute of Biochemistry, Lausanne branch, University of Lausanne; Irmler M, Thome M, Hahne M, Schneider P, Hofmann K, Steiner V, Bodmer JL, Schröter M, Burns K, Mattmann C, Rimoldi D, French LE, Tschopp J. Diakses tanggal 2010-10-26.

[3] (Inggris) "The role of cellular FLICE inhibitory protein (c-FLIP) in the pathogenesis and treatment of cancer". Cancer Research UK Institute for Cancer Studies, Division of Cancer Studies, Department of Pathology, The Medical School, University of Birmingham; Dutton A, Young LS, Murray PG. Diakses tanggal 2010-10-26.

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@@ Baris 1: / Baris 1: @@
-'''Protein FLICE-i''' ({{lang-en|FLICE-inhibitory protein, CASP8 and FADD-like apoptosis regulator, FADD-like IL-1beta-converting enzyme inhibitory protein, FLIP}}) adalah [[faktor transkripsi]] dengan berkas [[gen]]etik CFLAR pada [[kromosom 2 (manusia)|kromosom 2]] lokasi 2q33-q34,<ref>{{en}}{{cite web
+'''Protein FLICE-i''' ({{lang-en|FLICE-inhibitory protein, CASP8 and FADD-like apoptosis regulator, FADD-like IL-1beta-converting enzyme inhibitory protein, FLIP}}) adalah [[faktor transkripsi]] dengan berkas [[gen]]etik CFLAR pada [[kromosom 2 (manusia)|kromosom 2]] lokasi 2q33-q34,<ref>{{en}} {{cite web
 | url          = http://www.ncbi.nlm.nih.gov/gene/8837
 | title        = CFLAR CASP8 and FADD-like apoptosis regulator [ Homo sapiens ]
 | accessdate   = 2010-10-26
 | work         = Entrez Gene
-}}</ref> yang banyak terdapat pada [[jaringan otot]] dan [[jaringan limfoid]],<ref>{{en}}{{cite web
+}}</ref> yang banyak terdapat pada [[jaringan otot]] dan [[jaringan limfoid]],<ref>{{en}} {{cite web
 | url          = http://www.ncbi.nlm.nih.gov/pubmed/9217161
 | title        = Inhibition of death receptor signals by cellular FLIP
@@ Baris 11: / Baris 11: @@
 }}</ref> sebagai regulator [[apoptosis]].
-Overekspresi FLIP dapat melindungi [[sel tumor]] dari mekanisme [[apoptosis]].<ref>{{en}}{{cite web
+Overekspresi FLIP dapat melindungi [[sel tumor]] dari mekanisme [[apoptosis]].<ref>{{en}} {{cite web
 | url          = http://www.ncbi.nlm.nih.gov/pubmed/16441226
 | title        = The role of cellular FLICE inhibitory protein (c-FLIP) in the pathogenesis and treatment of cancer